About: The 3´ untranslated region of the chicken c-src protooncogene modulates gene expression

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About: The 3´ untranslated region of the chicken c-src protooncogene modulates gene expression Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Byly studovány účinky kuřecí c-src 3´UTR na genovou expresi. c-src 3´UTR snižovala in vivo tumorigenní potenciál mutant s aktivovaným src v kuřatech. To je v souladu s poznatkem, že c-src 3´UTR snižovala hladinu proteinu Src a src mRNA a luciferázovou aktivitu in vitro. Z našich výsledků vyplývá, že kuřecí c-src 3´UTR hraje roli v negativní regulaci genové exprese, a to transkripčně či posttranskripčně (cs) The chicken c-src 3´UTR effects on gene expression have been explored. The c-src 3´UTR decreased the in vivo tumorigenic potential of the src-activated mutants in chickens. This corresponds with the finding that the c-src 3´UTR reduced the Src protein and src mRNA levels and luciferase activity in vitro. Our results suggest that the chicken c-src 3´UTR plays a role in the negative control of gene expression, either transcriptionally or posttranscriptionally The chicken c-src 3´UTR effects on gene expression have been explored. The c-src 3´UTR decreased the in vivo tumorigenic potential of the src-activated mutants in chickens. This corresponds with the finding that the c-src 3´UTR reduced the Src protein and src mRNA levels and luciferase activity in vitro. Our results suggest that the chicken c-src 3´UTR plays a role in the negative control of gene expression, either transcriptionally or posttranscriptionally (en)
Title	3´-netranslatovaná oblast kuřecího protoonkogenu c-src moduluje genovou expresi (cs) The 3´ untranslated region of the chicken c-src protooncogene modulates gene expression The 3´ untranslated region of the chicken c-src protooncogene modulates gene expression (en)
skos:prefLabel	3´-netranslatovaná oblast kuřecího protoonkogenu c-src moduluje genovou expresi (cs) The 3´ untranslated region of the chicken c-src protooncogene modulates gene expression The 3´ untranslated region of the chicken c-src protooncogene modulates gene expression (en)
skos:notation	RIV/68378050:_____/03:00108995!RIV/2005/AV0/A23005/N
http://linked.open.../vavai/riv/strany	51;62
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA204/02/0407), P(GA524/01/0866), Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Hejnar, Jiří Trejbalová, Kateřina Plachý, Jiří Svoboda, Jan Geryk, Josef
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	636803
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/03:00108995
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	c-src 3´ untranslated region; chicken c-src (en)
http://linked.open.../riv/klicoveSlovo	c-src 3´ untranslated region chicken c-src
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[D4162F17CEF4]
http://linked.open...i/riv/nazevZdroje	Folia Biologica
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Nature of wasting disease accompanied by immunodeficiency produced in ducks by chicken leukosis virus V-src oncogenes the dominant players in a hierarchy of events leading to cancer
http://linked.open...UplatneniVysledku	2003
http://linked.open...v/svazekPeriodika	49
http://linked.open...iv/tvurceVysledku	Plachý, Jiří Svoboda, Jan Hejnar, Jiří Trejbalová, Kateřina Geryk, Josef Calothy, G. Dezélée, P.
http://linked.open...n/vavai/riv/zamer	Regulace a signální cesty uplatňující se v genové expresi, imunitě, onkogenezi, replikaci virů, tvorbě buněčných struktur, chování buněk, vývoji a oplození
issn	0015-5500
number of pages	12 (xsd:int)

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