About: Differing sensitivity of tumor cells to apoptosis induced by iron deprivation in vitro.

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About: Differing sensitivity of tumor cells to apoptosis induced by iron deprivation in vitro. Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We studied the sensitivity of tumor cells to the induction of apoptosis by iron deprivation. Iron deprivation was achieved by the employment of a defined iron-deficient culture medium. We conclude that some tumor cells in vitro are sensitive to apoptosis induction by iron deprivation, while other tumor cells are resistant. All the tumors found to be sensitive to iron deprivation in this study (four cell lines) are of hematopoietic origin. The mechanism of resistance to apoptosis induction by iron deprivation differs from the mechanism of resistance to thiol deprivation. We studied the sensitivity of tumor cells to the induction of apoptosis by iron deprivation. Iron deprivation was achieved by the employment of a defined iron-deficient culture medium. We conclude that some tumor cells in vitro are sensitive to apoptosis induction by iron deprivation, while other tumor cells are resistant. All the tumors found to be sensitive to iron deprivation in this study (four cell lines) are of hematopoietic origin. The mechanism of resistance to apoptosis induction by iron deprivation differs from the mechanism of resistance to thiol deprivation. (en)
Title	Differing sensitivity of tumor cells to apoptosis induced by iron deprivation in vitro. Differing sensitivity of tumor cells to apoptosis induced by iron deprivation in vitro. (en)
skos:prefLabel	Differing sensitivity of tumor cells to apoptosis induced by iron deprivation in vitro. Differing sensitivity of tumor cells to apoptosis induced by iron deprivation in vitro. (en)
skos:notation	RIV/68378050:_____/01:23010349!RIV/2003/AV0/A23003/N
http://linked.open.../vavai/riv/strany	450;458
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA301/97/1029), Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Kovář, Jan Valenta, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	677768
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/01:23010349
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	sensitivity to apoptosis; - apoptosis induction; - iron deprivation (en)
http://linked.open.../riv/klicoveSlovo	- apoptosis induction - iron deprivation sensitivity to apoptosis
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[DCE4390C3B2C]
http://linked.open...i/riv/nazevZdroje	In Vitro Cellular and Developmental Biology - Animal
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Mechanism of apoptosis induction by iron deprivation in tumor cells.
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	37
http://linked.open...iv/tvurceVysledku	Kovář, Jan Valenta, Tomáš Štýbrová, H.
http://linked.open...n/vavai/riv/zamer	Regulace a signální cesty uplatňující se v genové expresi, imunitě, onkogenezi, replikaci virů, tvorbě buněčných struktur, chování buněk, vývoji a oplození
issn	1071-2690
number of pages	9 (xsd:int)

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