About: Genetically modified dendritic cell-based cancer vaccines.

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About: Genetically modified dendritic cell-based cancer vaccines. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The capacity to present antigens, activate naive T cells and induce primary cellular immunity make DC attractive vehicles for delivery of therapeutic cancer vaccines. Genetically modified DC vaccines can be prepared by transfection with polynucleotides coding for oncoproteins, immunostimulatory cytokines and/or co-stimulatory molecules, transduction with recombinant viral vectors encoding these molecules and tumour cell-DC fusion. The therapeutic effects of these vaccines in vitro and in vivo are discussed. The capacity to present antigens, activate naive T cells and induce primary cellular immunity make DC attractive vehicles for delivery of therapeutic cancer vaccines. Genetically modified DC vaccines can be prepared by transfection with polynucleotides coding for oncoproteins, immunostimulatory cytokines and/or co-stimulatory molecules, transduction with recombinant viral vectors encoding these molecules and tumour cell-DC fusion. The therapeutic effects of these vaccines in vitro and in vivo are discussed. (en)
Title	Genetically modified dendritic cell-based cancer vaccines. Genetically modified dendritic cell-based cancer vaccines. (en)
skos:prefLabel	Genetically modified dendritic cell-based cancer vaccines. Genetically modified dendritic cell-based cancer vaccines. (en)
skos:notation	RIV/68378050:_____/01:23010339!RIV/2003/AV0/A23003/N
http://linked.open.../vavai/riv/strany	153;155
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NC5526), Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Bubeník, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	681081
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/01:23010339
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	dendritic cells; - cancer vaccines (en)
http://linked.open.../riv/klicoveSlovo	- cancer vaccines dendritic cells
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[42066C848875]
http://linked.open...i/riv/nazevZdroje	Folia Biologica (Praha)
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Combined therapy of minimal residual disease using IL-2 and GM-CSF as recombinant cytokines or genetically modified vaccines
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	47
http://linked.open...iv/tvurceVysledku	Bubeník, Jan
http://linked.open...n/vavai/riv/zamer	Regulace a signální cesty uplatňující se v genové expresi, imunitě, onkogenezi, replikaci virů, tvorbě buněčných struktur, chování buněk, vývoji a oplození
issn	0015-5500
number of pages	3 (xsd:int)

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