About: The functional interactions between CD98, beta 1-integrins, and CD147 in the induction of U937 homotypic aggregation.

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About: The functional interactions between CD98, beta 1-integrins, and CD147 in the induction of U937 homotypic aggregation. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Several of the CD98 antibodies induced homotypic aggregation of U937 cells without affecting cellular viability or growth. Some CD29 antibodies partially inhibited CD98-induced aggregation. Some CD98 antibodies were potent inhibitors of CD29-induced aggregation. Two antibodies to CD147 were also potent inhibitors of both the aggregation and the protein tyrosine phosphorylation induced via CD98 ligation. The results support a role for CD98 within a multimolecular unit that regulates cell aggregation. Several of the CD98 antibodies induced homotypic aggregation of U937 cells without affecting cellular viability or growth. Some CD29 antibodies partially inhibited CD98-induced aggregation. Some CD98 antibodies were potent inhibitors of CD29-induced aggregation. Two antibodies to CD147 were also potent inhibitors of both the aggregation and the protein tyrosine phosphorylation induced via CD98 ligation. The results support a role for CD98 within a multimolecular unit that regulates cell aggregation. (en)
Title	The functional interactions between CD98, beta 1-integrins, and CD147 in the induction of U937 homotypic aggregation. The functional interactions between CD98, beta 1-integrins, and CD147 in the induction of U937 homotypic aggregation. (en)
skos:prefLabel	The functional interactions between CD98, beta 1-integrins, and CD147 in the induction of U937 homotypic aggregation. The functional interactions between CD98, beta 1-integrins, and CD147 in the induction of U937 homotypic aggregation. (en)
skos:notation	RIV/68378050:_____/01:23010304!RIV/2003/AV0/A23003/N
http://linked.open.../vavai/riv/strany	374;382
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA310/99/0349), Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Hořejší, Václav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	680821
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/01:23010304
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	integrin; - CD98; - CD147 (en)
http://linked.open.../riv/klicoveSlovo	- CD147 - CD98 integrin
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[326B1C55B2A4]
http://linked.open...i/riv/nazevZdroje	Blood
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Low-affinity monoclonal antibodies as specific tolls targeting functionally important subsets of leukocyte surface receptors
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	98
http://linked.open...iv/tvurceVysledku	Hořejší, Václav Sagawa, K. Skubitz, K. M. Fox, D. A. Katz, D. R. Chain, B. Cho, J. Y.
http://linked.open...n/vavai/riv/zamer	Regulace a signální cesty uplatňující se v genové expresi, imunitě, onkogenezi, replikaci virů, tvorbě buněčných struktur, chování buněk, vývoji a oplození
issn	0006-4971
number of pages	9 (xsd:int)

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