About: Monoclonal Antibody to Human Sperm Acrosomal Protein.

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About: Monoclonal Antibody to Human Sperm Acrosomal Protein. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Monoclonal antibody designated Hs-14 was generated after immunization of BALB/c mice with acid extract of human sperm. In immunofluorescence the Hs-14 binds to acrosome of permeabilized sperm cells and recognizes some intra-acrosomal protein. Western blotting revealed that under non-reducing conditions the Hs-14 detects a protein with molecular mass of 220 kDa. Under reducing condition the Hs-14 recognizes peptide bands within the range from 55 kDa to 110 kDa. The antibody reacts also with sperm of other mammalian species. Using Hs-14 antibody it is possible to evaluate sperm pathology. Monoclonal antibody designated Hs-14 was generated after immunization of BALB/c mice with acid extract of human sperm. In immunofluorescence the Hs-14 binds to acrosome of permeabilized sperm cells and recognizes some intra-acrosomal protein. Western blotting revealed that under non-reducing conditions the Hs-14 detects a protein with molecular mass of 220 kDa. Under reducing condition the Hs-14 recognizes peptide bands within the range from 55 kDa to 110 kDa. The antibody reacts also with sperm of other mammalian species. Using Hs-14 antibody it is possible to evaluate sperm pathology. (en)
Title	Monoclonal Antibody to Human Sperm Acrosomal Protein. Monoclonal Antibody to Human Sperm Acrosomal Protein. (en)
skos:prefLabel	Monoclonal Antibody to Human Sperm Acrosomal Protein. Monoclonal Antibody to Human Sperm Acrosomal Protein. (en)
skos:notation	RIV/68378050:_____/00:23000003!RIV/2003/AV0/A23003/N
http://linked.open.../vavai/riv/strany	55;57
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GV524/96/K162), P(IZ3911), P(OE53/1), Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Pěknicová, Jana Geussová, Gizela Čapková, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	718077
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/00:23000003
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	N/A (en)
http://linked.open.../riv/klicoveSlovo	N/A
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[40696E045E2A]
http://linked.open...i/riv/nazevZdroje	Folia Biologica (Praha)
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	New diagnostic kit for fertility testing Cellular and molecular basis of oogenesis fertilization and embryonic development in mammals Differencial diagnostics of human sperm patholohy fir assistend reproduction
http://linked.open...UplatneniVysledku	2000
http://linked.open...v/svazekPeriodika	46
http://linked.open...iv/tvurceVysledku	Pěknicová, Jana Čapková, Jana Geussová, Gizela
http://linked.open...n/vavai/riv/zamer	Regulace a signální cesty uplatňující se v genové expresi, imunitě, onkogenezi, replikaci virů, tvorbě buněčných struktur, chování buněk, vývoji a oplození
issn	0015-5500
number of pages	3 (xsd:int)

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