About: Common and small molecules as the ultimate regulatory and effector mediators of antigen-specific transplantation reactions

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About: Common and small molecules as the ultimate regulatory and effector mediators of antigen-specific transplantation reactions Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The authors suggest that the functioning of common and small molecules with enzymatic activities, such as iNOS, arginase, HO-1 or IDO, the bioavailability of their suibstrates (L-arginin, tryptophan) and the action of their small gaseous products (NO, CO) can be the ultimate mechanisms responsible for the effector immune reactios. Thus, in spite of the high immunological specificity of the immune system, the small and common molecules are the important effector players ensuring the specidfic immune reactions. The authors suggest that the functioning of common and small molecules with enzymatic activities, such as iNOS, arginase, HO-1 or IDO, the bioavailability of their suibstrates (L-arginin, tryptophan) and the action of their small gaseous products (NO, CO) can be the ultimate mechanisms responsible for the effector immune reactios. Thus, in spite of the high immunological specificity of the immune system, the small and common molecules are the important effector players ensuring the specidfic immune reactions. (en)
Title	Common and small molecules as the ultimate regulatory and effector mediators of antigen-specific transplantation reactions Common and small molecules as the ultimate regulatory and effector mediators of antigen-specific transplantation reactions (en)
skos:prefLabel	Common and small molecules as the ultimate regulatory and effector mediators of antigen-specific transplantation reactions Common and small molecules as the ultimate regulatory and effector mediators of antigen-specific transplantation reactions (en)
skos:notation	RIV/68378041:_____/13:00397908!RIV14-MZ0-68378041
http://linked.open...avai/riv/aktivita	I P S Z
http://linked.open...avai/riv/aktivity	I, P(GAP301/11/1568), P(GAP304/11/0653), P(NT14102), S, Z(MSM0021620858)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Holáň, Vladimír Krulová, Magdalena
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	66025
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/13:00397908
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	immunoregulation; graft rejection; tolerance (en)
http://linked.open.../riv/klicoveSlovo	immunoregulation tolerance graft rejection
http://linked.open...odStatuVydavatele	HK - Zvláštní administrativní oblast Čínské lidové republiky Hongkong
http://linked.open...ontrolniKodProRIV	[2B0D6A482ED5]
http://linked.open...i/riv/nazevZdroje	World journal of transplantation
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Cellular aspects of transplantation tolerance Targeted differentiation and transdifferentiation of limbal and mesenchymal stem cells and their therapeutic applications in preclinical models A role of B lymphocytes in immune reactions after kidney transplantation
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	3
http://linked.open...iv/tvurceVysledku	Holáň, Vladimír Krulová, Magdaléna
http://linked.open...n/vavai/riv/zamer	Signaling and cellular response mechanisms
issn	2220-3230
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.5500/wjt.v3.i4.54

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