About: The combination of mesenchymal stem cells and a bone scaffold in the treatment of vertebral body defects

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About: The combination of mesenchymal stem cells and a bone scaffold in the treatment of vertebral body defects Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The safety and efficacy of a composite bioartificial graft based on a hydroxyapatite bone scaffold (CEM-OSTETIC) combined with human mesenchymal stem cells (MSCs) was evaluated in a rat model of vertebral body defects. Significant effect on the formation of new bone tissue in the defect a reduced inflammatory reaction was detected after combination of 5 mil MSC and scaffold. No substantial pathological changes or tumor formation after graft implantation were observed. The safety and efficacy of a composite bioartificial graft based on a hydroxyapatite bone scaffold (CEM-OSTETIC) combined with human mesenchymal stem cells (MSCs) was evaluated in a rat model of vertebral body defects. Significant effect on the formation of new bone tissue in the defect a reduced inflammatory reaction was detected after combination of 5 mil MSC and scaffold. No substantial pathological changes or tumor formation after graft implantation were observed. (en)
Title	The combination of mesenchymal stem cells and a bone scaffold in the treatment of vertebral body defects The combination of mesenchymal stem cells and a bone scaffold in the treatment of vertebral body defects (en)
skos:prefLabel	The combination of mesenchymal stem cells and a bone scaffold in the treatment of vertebral body defects The combination of mesenchymal stem cells and a bone scaffold in the treatment of vertebral body defects (en)
skos:notation	RIV/68378041:_____/13:00397075!RIV14-MZ0-68378041
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GAP304/10/0320), P(NT13477)
http://linked.open...iv/cisloPeriodika	12
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Syková, Eva Jendelová, Pavla Vaněček, Václav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	65962
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/13:00397075
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	vertebral body defect; mesenchymal stem cells; hydroxyapatite scaffold (en)
http://linked.open.../riv/klicoveSlovo	hydroxyapatite scaffold vertebral body defect mesenchymal stem cells
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[7647A5C1578C]
http://linked.open...i/riv/nazevZdroje	European Spine Journal
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	The use of the synthetic biomaterials in the treatment of the extensive skeletal defects in revision total hip arthroplasty Utilization of autologous mesenchymal cells in the posterolateral spinal fusion in the degenerative spine diseases: preclinical and clinical trial
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	22
http://linked.open...iv/tvurceVysledku	Jiroušek, Ondřej Syková, Eva Jendelová, Pavla Vaněček, Václav Šedý, Jiří Foltán, R. Klíma, K. Kohout, A. Štulík, J.
http://linked.open...ain/vavai/riv/wos	000327899100014
issn	0940-6719
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s00586-013-2991-2

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