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rdf:type
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Description
| - Gene expression levels are significantly regulated by DNA methylation. In this study the methylation profiles in children (7-15 years) with and without asthma from two regions with different levels of air pollution (a highly polluted Ostrava region and a control Prachatice region) were studied. Results demonstrate a significant impact of different environmental conditions on the DNA methylation patterns of children from the two regions. No difference in DNA methylation patterns was found between children with and without bronchial asthma in individual locations, but patterns in both asthmatic and healthy children differed between Ostrava and Prachatice. Further, differences in DNA methylation pattern depending on gender and urinary cotinine levels were observed. Other factors including lenght of gestation, birth weight and lenght of full breastfeeding are suggested as possible factors that can impact the DNA methylation pattern in future life.
- Gene expression levels are significantly regulated by DNA methylation. In this study the methylation profiles in children (7-15 years) with and without asthma from two regions with different levels of air pollution (a highly polluted Ostrava region and a control Prachatice region) were studied. Results demonstrate a significant impact of different environmental conditions on the DNA methylation patterns of children from the two regions. No difference in DNA methylation patterns was found between children with and without bronchial asthma in individual locations, but patterns in both asthmatic and healthy children differed between Ostrava and Prachatice. Further, differences in DNA methylation pattern depending on gender and urinary cotinine levels were observed. Other factors including lenght of gestation, birth weight and lenght of full breastfeeding are suggested as possible factors that can impact the DNA methylation pattern in future life. (en)
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Title
| - Factors affecting the 27K DNA methylation pattern in asthmatic and healthy children from locations with various environments
- Factors affecting the 27K DNA methylation pattern in asthmatic and healthy children from locations with various environments (en)
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skos:prefLabel
| - Factors affecting the 27K DNA methylation pattern in asthmatic and healthy children from locations with various environments
- Factors affecting the 27K DNA methylation pattern in asthmatic and healthy children from locations with various environments (en)
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skos:notation
| - RIV/68378041:_____/13:00395370!RIV14-GA0-68378041
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - I, P(GA13-13458S), P(GAP503/11/0084)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/68378041:_____/13:00395370
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - 27K BeadChip; air pollution; bronchial asthma (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Rössnerová, Andrea
- Rössner ml., Pavel
- Schmuczerová, Jana
- Šrám, Radim
- Dostál, Miroslav
- Tabashidze, Nana
- Gmuender, H.
- Tulupová, Elena
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.mrfmmm.2013.02.003
|