About: Control of the extracellular ionic environment and volume

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	It is evident that glial cells play an important role in different brain functions. Voltage- and ligand-activated channels and a number of transport mechanisms on the glial membrane allow for the maintenance of ionic and volume homeostasis, which in turn affect neuronal function. The production of extracellular matrix molecules by activated astrocytes further hinders already impaired diffusion and contributes to an increase in tortuosity. Astrocytes can thus be viewed as active elements in signal transmission as they affect both synaptic as well as extrasynaptic volume transmission. It is evident that glial cells play an important role in different brain functions. Voltage- and ligand-activated channels and a number of transport mechanisms on the glial membrane allow for the maintenance of ionic and volume homeostasis, which in turn affect neuronal function. The production of extracellular matrix molecules by activated astrocytes further hinders already impaired diffusion and contributes to an increase in tortuosity. Astrocytes can thus be viewed as active elements in signal transmission as they affect both synaptic as well as extrasynaptic volume transmission. (en)
Title	Control of the extracellular ionic environment and volume Control of the extracellular ionic environment and volume (en)
skos:prefLabel	Control of the extracellular ionic environment and volume Control of the extracellular ionic environment and volume (en)
skos:notation	RIV/68378041:_____/13:00388979!RIV14-GA0-68378041
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GA309/09/1597)
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Syková, Eva
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	66969
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/13:00388979
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	neurons; extracellular space; central nervous system (en)
http://linked.open.../riv/klicoveSlovo	extracellular space central nervous system neurons
http://linked.open...ontrolniKodProRIV	[C51EFF65A88B]
http://linked.open...i/riv/mistoVydani	New York
http://linked.open...i/riv/nazevZdroje	Neuroglia
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...v/pocetStranKnihy	930 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...vavai/riv/projekt	Role of the extracelullar matrix in the extracelullar space diffusion parameter changes during aging and the metabolic syndrome
http://linked.open...UplatneniVysledku	2013
http://linked.open...iv/tvurceVysledku	Syková, Eva
number of pages	13 (xsd:int)
http://bibframe.org/vocab/doi	10.1093/med/9780199794591.003.0034
http://purl.org/ne...btex#hasPublisher	Oxford University Press
https://schema.org/isbn	978-0-19-979459-1

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