About: High tryptophan diet reduces CA1 intraneuronal ss-amyloid in the triple transgenic mouse model of Alzheimer's disease.

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: High tryptophan diet reduces CA1 intraneuronal ss-amyloid in the triple transgenic mouse model of Alzheimer's disease. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Alzheimer's disease (AD) is a progressive neurodegenerative disease that impairs mnesic functions. The histopathology of the disease is manifested by the accumulation of intracellular β-amyloid (Aβ) and subsequent formation of neuritic plaques as well as the presence neurofibrillary tangles in specific brain regions associated with learning and memory including the hippocampus. Our results show that increased dietary TrP intake reduces intraneuronal Aβ load in the 3xTg-AD mouse model of AD, suggesting that enhanced TrP intake and in consequence a potential increase in 5-HT neurotransmission may be effective in reducing plaque pathology in AD. Alzheimer's disease (AD) is a progressive neurodegenerative disease that impairs mnesic functions. The histopathology of the disease is manifested by the accumulation of intracellular β-amyloid (Aβ) and subsequent formation of neuritic plaques as well as the presence neurofibrillary tangles in specific brain regions associated with learning and memory including the hippocampus. Our results show that increased dietary TrP intake reduces intraneuronal Aβ load in the 3xTg-AD mouse model of AD, suggesting that enhanced TrP intake and in consequence a potential increase in 5-HT neurotransmission may be effective in reducing plaque pathology in AD. (en)
Title	High tryptophan diet reduces CA1 intraneuronal ss-amyloid in the triple transgenic mouse model of Alzheimer's disease. High tryptophan diet reduces CA1 intraneuronal ss-amyloid in the triple transgenic mouse model of Alzheimer's disease. (en)
skos:prefLabel	High tryptophan diet reduces CA1 intraneuronal ss-amyloid in the triple transgenic mouse model of Alzheimer's disease. High tryptophan diet reduces CA1 intraneuronal ss-amyloid in the triple transgenic mouse model of Alzheimer's disease. (en)
skos:notation	RIV/68378041:_____/12:00384005!RIV13-AV0-68378041
http://linked.open...avai/riv/aktivita	I P Z
http://linked.open...avai/riv/aktivity	I, P(GA305/08/1384), P(GA309/09/1696), P(GAP304/11/0184), Z(AV0Z50390703)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Rodríguez Arellano, Jose Julio
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	138983
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/12:00384005
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Alzheimer's disease; hippocampus; L-tryptophan diet (en)
http://linked.open.../riv/klicoveSlovo	hippocampus L-tryptophan diet Alzheimer's disease
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[7199A6DEFF75]
http://linked.open...i/riv/nazevZdroje	Aging Cell
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Age-related changes in the structure and function of astrocytes Pathological potential of astroglia in Alzheimer disease Využití mesenchymových kmenových buněk v léčbě Alzheimerovy choroby
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	11
http://linked.open...iv/tvurceVysledku	Noristani, H. N. Rodríguez Arellano, Jose Julio Verkhratsky, A.
http://linked.open...ain/vavai/riv/wos	000308871400010
http://linked.open...n/vavai/riv/zamer	New biotechnologies, nanomaterials and stem cells for use in regenerative medicine
issn	1474-9718
number of pages	13 (xsd:int)
http://bibframe.org/vocab/doi	10.1111/j.1474-9726.2012.00845.x

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software