About: The use of dopamine-hyaluronate associate-coated maghemite nanoparticles to label cells

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Sodium hyaluronate (HA) was associated with dopamine (DPA) and introduced as a coating for maghemite (γ-Fe2O3) nanoparticles obtained by the coprecipitation of iron(II) and iron(III) chlorides and oxidation with sodium hypochlorite. The effects of the DPA anchorage of HA on the γ-Fe2O3 surface on the physicochemical properties of the resulting colloids were investigated. Nanoparticles coated at three different DPA-HA/γ-Fe2O3 and DPA/HA ratios were chosen for experiments with rat bone marrow mesenchymal stem cells and human chondrocytes. The efficiency of mesenchymal stem cell labeling was analyzed. From among the investigated samples, efficient cell labeling was achieved by using DPA-HA-γ-Fe2O3 nanoparticles with DPA-HA/γ-Fe2O3 = 0.45 (weight/weight) and DPA/HA = 0.038 (weight/weight) ratios. The particles were used as a contrast agent in magnetic resonance imaging for the labeling and visualization of cells. Sodium hyaluronate (HA) was associated with dopamine (DPA) and introduced as a coating for maghemite (γ-Fe2O3) nanoparticles obtained by the coprecipitation of iron(II) and iron(III) chlorides and oxidation with sodium hypochlorite. The effects of the DPA anchorage of HA on the γ-Fe2O3 surface on the physicochemical properties of the resulting colloids were investigated. Nanoparticles coated at three different DPA-HA/γ-Fe2O3 and DPA/HA ratios were chosen for experiments with rat bone marrow mesenchymal stem cells and human chondrocytes. The efficiency of mesenchymal stem cell labeling was analyzed. From among the investigated samples, efficient cell labeling was achieved by using DPA-HA-γ-Fe2O3 nanoparticles with DPA-HA/γ-Fe2O3 = 0.45 (weight/weight) and DPA/HA = 0.038 (weight/weight) ratios. The particles were used as a contrast agent in magnetic resonance imaging for the labeling and visualization of cells. (en)
Title	The use of dopamine-hyaluronate associate-coated maghemite nanoparticles to label cells The use of dopamine-hyaluronate associate-coated maghemite nanoparticles to label cells (en)
skos:prefLabel	The use of dopamine-hyaluronate associate-coated maghemite nanoparticles to label cells The use of dopamine-hyaluronate associate-coated maghemite nanoparticles to label cells (en)
skos:notation	RIV/68378041:_____/12:00375923!RIV13-AV0-68378041
http://linked.open...avai/riv/aktivita	I P Z
http://linked.open...avai/riv/aktivity	I, P(1M0538), P(GA203/09/1242), P(GAP304/12/1370), P(GCP207/12/J013), Z(AV0Z40500505), Z(AV0Z50390703)
http://linked.open...iv/cisloPeriodika	16 March
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Syková, Eva Jendelová, Pavla Vaněček, Václav Lesný, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	176342
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/12:00375923
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	nanoparticles; dopamine; hyaluronate (en)
http://linked.open.../riv/klicoveSlovo	nanoparticles dopamine hyaluronate
http://linked.open...odStatuVydavatele	NZ - Nový Zéland
http://linked.open...ontrolniKodProRIV	[ADC441F00D96]
http://linked.open...i/riv/nazevZdroje	International Journal of Nanomedicine
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Surface-modified magnetic nanoparticles for cell labeling and in vivo and in vitro diagnostics Center for Cell Therapy and Tissue Repair Superparamagnetic iron-oxide nanoparticles for cellular imaging and their effect on genotoxicity, cytotocixity and stem cell differentiation. Innovative multifunctional magnetic nano- and microparticles for cell diagnostics
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	7
http://linked.open...iv/tvurceVysledku	Horák, Daniel Syková, Eva Herynek, V. Jendelová, Pavla Vaněček, Václav Proks, Vladimír Babič, Michal Lesný, Petr
http://linked.open...ain/vavai/riv/wos	000302728100001
http://linked.open...n/vavai/riv/zamer	Progresivní makromolekulární materiály a supramolekulární systémy: syntéza a studium vlastností, jevů a možností využití pro speciální aplikace a moderní technologie New biotechnologies, nanomaterials and stem cells for use in regenerative medicine
issn	1178-2013
number of pages	14 (xsd:int)
http://bibframe.org/vocab/doi	10.2147/IJN.S28658

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