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Description
| - Previously we have identified two genomic regions in which pairs of tagging-single nucleotide polymorphisms (tagSNPs) are associated with disease in genome-wide association studies of colorectal cancer. Simple genotyping of additional sample sets at the original tagSNPs didn’t show expected results, we therefore undertook more detailed analyses, using imputation, logistic regression, genealogical analysis using the GENECLUSTER program, and haplotype analysis. We revealed new facts about the situation in 1q41 and 12q13.13 regions and found strong evidence for candidate functional variants.
- Previously we have identified two genomic regions in which pairs of tagging-single nucleotide polymorphisms (tagSNPs) are associated with disease in genome-wide association studies of colorectal cancer. Simple genotyping of additional sample sets at the original tagSNPs didn’t show expected results, we therefore undertook more detailed analyses, using imputation, logistic regression, genealogical analysis using the GENECLUSTER program, and haplotype analysis. We revealed new facts about the situation in 1q41 and 12q13.13 regions and found strong evidence for candidate functional variants. (en)
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Title
| - Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13
- Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13 (en)
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skos:prefLabel
| - Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13
- Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13 (en)
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skos:notation
| - RIV/68378041:_____/12:00373891!RIV13-AV0-68378041
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/68378041:_____/12:00373891
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - tagging-single nucleotide polymorphisms; colorectal cancer; candidate functional variant (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Vodička, Pavel
- Li, L.
- Jones, A. M.
- Aaltonen, T.
- Carracedo, A.
- Castells, A.
- Castellví-Bel, S.
- Dunlop, M.
- Lipton, L.
- Morreau, H.
- Ruiz-Ponte, C.
- Sieber, O.
- Tomplinson, P. M.
- Baird, P. N.
- Carvajal-Carmona, L. G.
- Casey, G.
- Cazier, J. B.
- Cheadle, J.
- Fernandez-Rozadilla, C.
- Gibbs, P.
- Houlston, R. S.
- Howarth, K. M.
- Kerr, D. J.
- Martin, N. G.
- Montgomery, G. W.
- Pharoah, P.
- Spain, S. L.
- Su, Z.
- Wezel, T.
- Williams, J.
- Young, J.
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://bibframe.org/vocab/doi
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