About: HVRII of mtDNA in Cord Blood Cells of Newborn Children and in Their Saliva 10 Years Later

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Comparison of hypervariable region II nucleotide sequences of mitochondrial DNA obtained from cord blood cells and saliva cells of the same individual at birth and after ten years showed a few differences at the co-called mutation hot spots (three transitions and three indels within the C-tract). The personal identity of samples was proved by short tandem repeat profiling. Comparison of individuals living in two regions with different air pollution, however, did not reveal statistically significantly increased number of mutations in the population from the region of poorer environmental conditions, although indicating such tendency. Comparison of hypervariable region II nucleotide sequences of mitochondrial DNA obtained from cord blood cells and saliva cells of the same individual at birth and after ten years showed a few differences at the co-called mutation hot spots (three transitions and three indels within the C-tract). The personal identity of samples was proved by short tandem repeat profiling. Comparison of individuals living in two regions with different air pollution, however, did not reveal statistically significantly increased number of mutations in the population from the region of poorer environmental conditions, although indicating such tendency. (en)
Title	HVRII of mtDNA in Cord Blood Cells of Newborn Children and in Their Saliva 10 Years Later HVRII of mtDNA in Cord Blood Cells of Newborn Children and in Their Saliva 10 Years Later (en)
skos:prefLabel	HVRII of mtDNA in Cord Blood Cells of Newborn Children and in Their Saliva 10 Years Later HVRII of mtDNA in Cord Blood Cells of Newborn Children and in Their Saliva 10 Years Later (en)
skos:notation	RIV/68378041:_____/11:00360462!RIV12-MZP-68378041
http://linked.open...avai/riv/aktivita	I P S Z
http://linked.open...avai/riv/aktivity	I, P(SL/5/160/05), S, Z(AV0Z50390512)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Šrám, Radim Topinka, Jan Schmuczerová, Jana Dostál, Miroslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	203023
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/11:00360462
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	mitochondrial DNA; cord blood; saliva (en)
http://linked.open.../riv/klicoveSlovo	cord blood mitochondrial DNA saliva
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[835F2A911A38]
http://linked.open...i/riv/nazevZdroje	Folia Biologica
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Environmental factors and health
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	56
http://linked.open...iv/tvurceVysledku	Schmuczerová, Jana Topinka, Jan Šrám, Radim Dostál, Miroslav Brdička, R. Kujanová, M. Töröková, P. Čechová, H.
http://linked.open...ain/vavai/riv/wos	000288623700005
http://linked.open...n/vavai/riv/zamer	Molekulární, buněčné a systémové mechanizmy závažných onemocnění lidského organizmu, jejich diagnostika, terapie a farmakoterapie
issn	0015-5500
number of pages	4 (xsd:int)

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