About: Fluorescent magnetic nanoparticles for biomedical applications

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Fluorescent magnetic nanoparticles for biomedical applications Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The simultaneous combination of optical and magnetic resonance imaging (MRI) would greatly benefit in vivo disease diagnosis as well as in situ monitoring of living cells. In order to design dual detection of cells involving simultaneous imaging by fluorescent microscopy and MRI, nanoparticles with two reporters, a fluorescent dye and a superparamagnetic core, included in one particle were synthesized and characterized. The γ-Fe2O3 nanoparticles obtained by coprecipitation and oxidation were coated with silica (SiO2) or carboxymethyl chitosan (CMCS) and labeled with fluorescein isothiocyanate (FITC). The fluorescent label was covalently bound to the nanoparticles and was not quenched by the iron oxide core. The nanoparticles successfully labeled rat mesenchymal stem cells (rMSCs) in vitro. Relaxation time measurements found large amounts of iron inside the cells with FITC-labeled γ-Fe2O3–SiO2-AP nanoparticles. The simultaneous combination of optical and magnetic resonance imaging (MRI) would greatly benefit in vivo disease diagnosis as well as in situ monitoring of living cells. In order to design dual detection of cells involving simultaneous imaging by fluorescent microscopy and MRI, nanoparticles with two reporters, a fluorescent dye and a superparamagnetic core, included in one particle were synthesized and characterized. The γ-Fe2O3 nanoparticles obtained by coprecipitation and oxidation were coated with silica (SiO2) or carboxymethyl chitosan (CMCS) and labeled with fluorescein isothiocyanate (FITC). The fluorescent label was covalently bound to the nanoparticles and was not quenched by the iron oxide core. The nanoparticles successfully labeled rat mesenchymal stem cells (rMSCs) in vitro. Relaxation time measurements found large amounts of iron inside the cells with FITC-labeled γ-Fe2O3–SiO2-AP nanoparticles. (en)
Title	Fluorescent magnetic nanoparticles for biomedical applications Fluorescent magnetic nanoparticles for biomedical applications (en)
skos:prefLabel	Fluorescent magnetic nanoparticles for biomedical applications Fluorescent magnetic nanoparticles for biomedical applications (en)
skos:notation	RIV/68378041:_____/11:00359777!RIV12-AV0-68378041
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0538), P(7E09109), P(GA203/09/1242), P(GD309/08/H079), P(KAN200200651), P(KAN201110651), Z(AV0Z40500505), Z(AV0Z50390703)
http://linked.open...iv/cisloPeriodika	21
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Syková, Eva Jendelová, Pavla Turnovcová, Karolína
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	200032
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/11:00359777
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	magnetic; fluorescent; stem cells (en)
http://linked.open.../riv/klicoveSlovo	stem cells fluorescent magnetic
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[8A64CF84D2BD]
http://linked.open...i/riv/nazevZdroje	Journal of Materials Chemistry
http://linked.open...in/vavai/riv/obor	CD
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Integrated Micro-Nano-Opto Fluidic systems for high-content diagnosis and studies of rare cancer cells Surface-modified magnetic nanoparticles for cell labeling and in vivo and in vitro diagnostics PhD program in neuroscience Center for Cell Therapy and Tissue Repair Nanoparticulate and supramolecular systems for targeted drug delivery Combined contrast agents for molecular MR imaging
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	21
http://linked.open...iv/tvurceVysledku	Hrubý, Martin Horák, Daniel Syková, Eva Trchová, Miroslava Herynek, V. Jendelová, Pavla Beneš, Milan J. Chekina, Nataliya Turnovcová, Karolína
http://linked.open...ain/vavai/riv/wos	000290670000017
http://linked.open...n/vavai/riv/zamer	Progresivní makromolekulární materiály a supramolekulární systémy: syntéza a studium vlastností, jevů a možností využití pro speciální aplikace a moderní technologie New biotechnologies, nanomaterials and stem cells for use in regenerative medicine
issn	0959-9428
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1039/C1JM10621J

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software