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Description
| - Nanofibrous layers of reproducible thickness and structure (Nanospider technology) were employed as carriers for hepatocytes and their efficiency were evaluated in a laboratory bioreactor. The construction of the functional hepatal bioreactor is particularly given by the positive response of hepatocyte cells to the used carrier layer as well as by the cell morphology, their viability and biological activity in certain period of time. We compared cell growth on collagen with nanofibres electrospun from copolymer (HEMA/EOEMA) and from differently prepared polycaprolactone (PCL) layers. In both cases, the cells showed better morphology or better growth the on controls (collagen). The results obtained in laboratory bioreactor proved the biochemical functionality of the studied system.
- Nanofibrous layers of reproducible thickness and structure (Nanospider technology) were employed as carriers for hepatocytes and their efficiency were evaluated in a laboratory bioreactor. The construction of the functional hepatal bioreactor is particularly given by the positive response of hepatocyte cells to the used carrier layer as well as by the cell morphology, their viability and biological activity in certain period of time. We compared cell growth on collagen with nanofibres electrospun from copolymer (HEMA/EOEMA) and from differently prepared polycaprolactone (PCL) layers. In both cases, the cells showed better morphology or better growth the on controls (collagen). The results obtained in laboratory bioreactor proved the biochemical functionality of the studied system. (en)
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Title
| - Specific cell cultivation on nanofibrous layer
- Specific cell cultivation on nanofibrous layer (en)
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skos:prefLabel
| - Specific cell cultivation on nanofibrous layer
- Specific cell cultivation on nanofibrous layer (en)
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skos:notation
| - RIV/68378041:_____/10:00350418!RIV11-GA0-68378041
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA304/07/1129), P(KJB400500902), Z(AV0Z40500505), Z(AV0Z50390703)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/68378041:_____/10:00350418
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - hepatocytes; hepatal bioreactor; bioartifical liver assist device (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - CH - Švýcarská konfederace
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Advances in Science and Technology
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Hobzová, Radka
- Michálek, Jiří
- Přádný, Martin
- Syková, Eva
- Jendelová, Pavla
- Lubasová, D.
- Martinová, L.
- Lesný, Petr
- Mareková, Dana
- Kostecká, Petra
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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