About: Specific cell cultivation on nanofibrous layer

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Nanofibrous layers of reproducible thickness and structure (Nanospider technology) were employed as carriers for hepatocytes and their efficiency were evaluated in a laboratory bioreactor. The construction of the functional hepatal bioreactor is particularly given by the positive response of hepatocyte cells to the used carrier layer as well as by the cell morphology, their viability and biological activity in certain period of time. We compared cell growth on collagen with nanofibres electrospun from copolymer (HEMA/EOEMA) and from differently prepared polycaprolactone (PCL) layers. In both cases, the cells showed better morphology or better growth the on controls (collagen). The results obtained in laboratory bioreactor proved the biochemical functionality of the studied system. Nanofibrous layers of reproducible thickness and structure (Nanospider technology) were employed as carriers for hepatocytes and their efficiency were evaluated in a laboratory bioreactor. The construction of the functional hepatal bioreactor is particularly given by the positive response of hepatocyte cells to the used carrier layer as well as by the cell morphology, their viability and biological activity in certain period of time. We compared cell growth on collagen with nanofibres electrospun from copolymer (HEMA/EOEMA) and from differently prepared polycaprolactone (PCL) layers. In both cases, the cells showed better morphology or better growth the on controls (collagen). The results obtained in laboratory bioreactor proved the biochemical functionality of the studied system. (en)
Title	Specific cell cultivation on nanofibrous layer Specific cell cultivation on nanofibrous layer (en)
skos:prefLabel	Specific cell cultivation on nanofibrous layer Specific cell cultivation on nanofibrous layer (en)
skos:notation	RIV/68378041:_____/10:00350418!RIV11-GA0-68378041
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA304/07/1129), P(KJB400500902), Z(AV0Z40500505), Z(AV0Z50390703)
http://linked.open...iv/cisloPeriodika	-
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Syková, Eva Kostecká, Petra Jendelová, Pavla Mareková, Dana Lesný, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	289041
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/10:00350418
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	hepatocytes; hepatal bioreactor; bioartifical liver assist device (en)
http://linked.open.../riv/klicoveSlovo	hepatocytes bioartifical liver assist device hepatal bioreactor
http://linked.open...odStatuVydavatele	CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV	[4B332A1E7692]
http://linked.open...i/riv/nazevZdroje	Advances in Science and Technology
http://linked.open...in/vavai/riv/obor	CD
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Polarised cultures of hepatocytes and mesenchymal cells on the nanofiber membranes in the experimental bioreactor Surface modification of polymer supports targeted for specific cell cultivation
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	76
http://linked.open...iv/tvurceVysledku	Hobzová, Radka Michálek, Jiří Přádný, Martin Syková, Eva Jendelová, Pavla Lubasová, D. Martinová, L. Lesný, Petr Mareková, Dana Kostecká, Petra
http://linked.open...n/vavai/riv/zamer	Progresivní makromolekulární materiály a supramolekulární systémy: syntéza a studium vlastností, jevů a možností využití pro speciální aplikace a moderní technologie New biotechnologies, nanomaterials and stem cells for use in regenerative medicine
issn	1662-0356
number of pages	4 (xsd:int)

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