About: Chronic Treatment with NGF Induces Spontaneous Fluctuations of Intracellular Ca(2+) in Icilin-Sensitive Dorsal Root Ganglion Neurons of the Rat     Goto   Sponge   NotDistinct   Permalink

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  • These results suggest that neurons expressing both capsaicin- and icilin-sensitive TRP channels are susceptible to NGF and become hyperexcitable and that Ca2+ influx through voltage-gated Ca2+ channels is the major source contributing to the [Ca2+)]i fluctuations. Since such DRG neurons could play a physiological role as nociceptors, the NGF-induced spontaneous activity of DRG neurons may be the underlying mechanism of neuropathic pain
  • These results suggest that neurons expressing both capsaicin- and icilin-sensitive TRP channels are susceptible to NGF and become hyperexcitable and that Ca2+ influx through voltage-gated Ca2+ channels is the major source contributing to the [Ca2+)]i fluctuations. Since such DRG neurons could play a physiological role as nociceptors, the NGF-induced spontaneous activity of DRG neurons may be the underlying mechanism of neuropathic pain (en)
Title
  • Chronic Treatment with NGF Induces Spontaneous Fluctuations of Intracellular Ca(2+) in Icilin-Sensitive Dorsal Root Ganglion Neurons of the Rat
  • Chronic Treatment with NGF Induces Spontaneous Fluctuations of Intracellular Ca(2+) in Icilin-Sensitive Dorsal Root Ganglion Neurons of the Rat (en)
skos:prefLabel
  • Chronic Treatment with NGF Induces Spontaneous Fluctuations of Intracellular Ca(2+) in Icilin-Sensitive Dorsal Root Ganglion Neurons of the Rat
  • Chronic Treatment with NGF Induces Spontaneous Fluctuations of Intracellular Ca(2+) in Icilin-Sensitive Dorsal Root Ganglion Neurons of the Rat (en)
skos:notation
  • RIV/68378041:_____/10:00349380!RIV11-AV0-68378041
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z50390703)
http://linked.open...iv/cisloPeriodika
  • 12
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
  • Dayanithi, Govindan
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 250720
http://linked.open...ai/riv/idVysledku
  • RIV/68378041:_____/10:00349380
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • capsaicin; sensory neuron; TRPA1 (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • JP - Japonsko
http://linked.open...ontrolniKodProRIV
  • [B52E5FB1F80A]
http://linked.open...i/riv/nazevZdroje
  • Journal of Veterinary Medical Science
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 72
http://linked.open...iv/tvurceVysledku
  • Dayanithi, Govindan
  • Kitamura, N.
  • Kayano, T.
  • Shibuya, I.
  • Moriya, A.
  • Ozaki, Y.
http://linked.open...ain/vavai/riv/wos
  • 000285986700001
http://linked.open...n/vavai/riv/zamer
issn
  • 0916-7250
number of pages
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