About: Metabolic changes in the rat brain after a photochemical lesion treated by stem cell transplantation assessed by 1H MRS

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About: Metabolic changes in the rat brain after a photochemical lesion treated by stem cell transplantation assessed by 1H MRS Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The article describes the metabolic changes in the rat brain after a photochemical lesion treated by stem cell transplantation. 1H MRS revealed a gradual recovery of the damaged tissue; however, we found no significant differences in metabolite concentrations in the lesioned hemisphere between treated and untreated animals. Higher concentrations of glutamate and N-acetyl aspartate were found in the contralateral hemisphere in cell-treated animals compared to untreated ones. Lesioned animals showed neurogenesis in the contralateral hemisphere; the number of newly generated cells in stem cell-treated animals was 50% higher than that observed in untreated animals. The article describes the metabolic changes in the rat brain after a photochemical lesion treated by stem cell transplantation. 1H MRS revealed a gradual recovery of the damaged tissue; however, we found no significant differences in metabolite concentrations in the lesioned hemisphere between treated and untreated animals. Higher concentrations of glutamate and N-acetyl aspartate were found in the contralateral hemisphere in cell-treated animals compared to untreated ones. Lesioned animals showed neurogenesis in the contralateral hemisphere; the number of newly generated cells in stem cell-treated animals was 50% higher than that observed in untreated animals. (en)
Title	Metabolic changes in the rat brain after a photochemical lesion treated by stem cell transplantation assessed by 1H MRS Metabolic changes in the rat brain after a photochemical lesion treated by stem cell transplantation assessed by 1H MRS (en)
skos:prefLabel	Metabolic changes in the rat brain after a photochemical lesion treated by stem cell transplantation assessed by 1H MRS Metabolic changes in the rat brain after a photochemical lesion treated by stem cell transplantation assessed by 1H MRS (en)
skos:notation	RIV/68378041:_____/09:00332235!RIV10-MSM-68378041
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0538), P(GA309/06/1594), P(KAN201110651), P(LC554), Z(AV0Z50390703), Z(MZ0IKEM2005)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Syková, Eva Růžičková, Kateřina Jendelová, Pavla
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	325560
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/09:00332235
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	mesenchymal stem cell transplantation; magnetic resonance spectroscopy; rats (en)
http://linked.open.../riv/klicoveSlovo	magnetic resonance spectroscopy rats mesenchymal stem cell transplantation
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[D7DCC6A35F57]
http://linked.open...i/riv/nazevZdroje	Magnetic Resonance Materials in Physics, Biology and Medicine
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Center for Cell Therapy and Tissue Repair Neuroscience Centre Cellular contrast agents for MR imaging Combined contrast agents for molecular MR imaging
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	22
http://linked.open...iv/tvurceVysledku	Syková, Eva Hájek, M. Herynek, V. Jendelová, Pavla Růžičková, Kateřina
http://linked.open...ain/vavai/riv/wos	000268903800002
http://linked.open...n/vavai/riv/zamer	New biotechnologies, nanomaterials and stem cells for use in regenerative medicine Výzkum kardiovaskulárních nemocí, diabetu a transplantace životně důležitých orgánů
issn	0968-5243
number of pages	10 (xsd:int)

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