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Description
  • Ultrastrukturálně jsme charakterizovali dynamiku syntézy DNA v synchronizovaných HeLa buňkách nacházejících se v mid-S fázi buněčného cyklu. Zjistili jsme, že replikace DNA v buněčném jádře je soustředěna do ohnisek. Naše výsledky podporují myšlenku, že centra syntézy DNA jsou fixována, zatímco chromatinové smyčky se více či méně volně pohybují (cs)
  • We have characterized the dynamics of DNA synthesis in synchronized mid-S-phase HeLa cells. These results demonstrate that DNA replication is compartmentalized within cell nuclei at the level of DNA foci and support the view that the synthetic centers are spatially constrained while the chromatin loops are dynamic during DNA synthesis
  • We have characterized the dynamics of DNA synthesis in synchronized mid-S-phase HeLa cells. These results demonstrate that DNA replication is compartmentalized within cell nuclei at the level of DNA foci and support the view that the synthetic centers are spatially constrained while the chromatin loops are dynamic during DNA synthesis (en)
Title
  • Dynamics of DNA replication: an ultrastructural study
  • Dynamics of DNA replication: an ultrastructural study (en)
  • Dynamika replikace DNA: ultrastrukturální náhled (cs)
skos:prefLabel
  • Dynamics of DNA replication: an ultrastructural study
  • Dynamics of DNA replication: an ultrastructural study (en)
  • Dynamika replikace DNA: ultrastrukturální náhled (cs)
skos:notation
  • RIV/68378041:_____/04:00109657!RIV/2005/AV0/A19005/N
http://linked.open.../vavai/riv/strany
  • 279;289
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(IAA5039701), Z(AV0Z5039906)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 561483
http://linked.open...ai/riv/idVysledku
  • RIV/68378041:_____/04:00109657
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http://linked.open.../riv/klicovaSlova
  • DNA replication (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [841E95F5F102]
http://linked.open...i/riv/nazevZdroje
  • Journal of Structural Biology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 148
http://linked.open...iv/tvurceVysledku
  • Hozák, Pavel
  • Janáček, Jiří
  • Hodný, Zdeněk
  • Philimonenko, Anatoly
  • Cook, P. R.
  • Jackson, D. A.
http://linked.open...n/vavai/riv/zamer
issn
  • 1047-8477
number of pages
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