About: Regulation of mGlu4 metabotropic glutamate receptor signaling by type-2 G-protein coupled receptor kinase (GRK2)

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About: Regulation of mGlu4 metabotropic glutamate receptor signaling by type-2 G-protein coupled receptor kinase (GRK2) Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	V našich experimentech jsme zkoumali roli GRK2 v homologní desentizaci Mglu4. Zjistili jsme že aktivace receptoru stimuluje nejméně dvě různé signální kaskády“ cAMP a MAPK (cs) We examined the role of G-protein coupled receptor kinase-2 (GRK2) in the homologous desensitization of mGlu4 metabotropic glutamate receptors transiently expressed in human embryonic kidney (HEK) 293 cells. Receptor activation with agonist stimulated at least two distinct signaling pathways: inhibition of cAMP formation and activation of the mitogen-activated protein kinase (MAPK) pathway. We examined the role of G-protein coupled receptor kinase-2 (GRK2) in the homologous desensitization of mGlu4 metabotropic glutamate receptors transiently expressed in human embryonic kidney (HEK) 293 cells. Receptor activation with agonist stimulated at least two distinct signaling pathways: inhibition of cAMP formation and activation of the mitogen-activated protein kinase (MAPK) pathway. (en)
Title	Regulation of mGlu4 metabotropic glutamate receptor signaling by type-2 G-protein coupled receptor kinase (GRK2) Regulace mGluR4 metabotropního glutamátového receptoru typem 2 G-protein spřažené kinázy GRK2 (cs) Regulation of mGlu4 metabotropic glutamate receptor signaling by type-2 G-protein coupled receptor kinase (GRK2) (en)
skos:prefLabel	Regulation of mGlu4 metabotropic glutamate receptor signaling by type-2 G-protein coupled receptor kinase (GRK2) Regulace mGluR4 metabotropního glutamátového receptoru typem 2 G-protein spřažené kinázy GRK2 (cs) Regulation of mGlu4 metabotropic glutamate receptor signaling by type-2 G-protein coupled receptor kinase (GRK2) (en)
skos:notation	RIV/68378041:_____/04:00100996!RIV/2005/AV0/A19005/N
http://linked.open.../vavai/riv/strany	1103;1110
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z5039906)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Blahoš, Jaroslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	584096
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/04:00100996
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	glutamate receptor (en)
http://linked.open.../riv/klicoveSlovo	glutamate receptor
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[46C4865C7E55]
http://linked.open...i/riv/nazevZdroje	Molecular Pharmacology
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	65
http://linked.open...iv/tvurceVysledku	Blahoš, Jaroslav Capobianco, L. De Blasi, A. Di Giorgi Gereviny, V. Iacovelli, L. Iula, M. Melchiorri, D. Nicoletti, F. Picascia, A.
http://linked.open...n/vavai/riv/zamer	The molecular and cellular basis of selected human diseases, mechanisms of normal and pathological function, principles of diagnosis and therapy
issn	0026-895X
number of pages	8 (xsd:int)

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