About: FGF-2 expression and its action in human leukemia and lymphoma cell lines.     Goto   Sponge   NotDistinct   Permalink

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  • It was shown that while the majority of human leukemia and lymphoma cell lines synthesizes low molecular mass FGF-2, its release is generally insufficient. However, several cell lines display prerequisites to respond to the extracellular FGF-2 that could be produced by other cell types. Importantly, in a majority of cell lines was found concomitant expression of two potent antiapoptotic molecules, high molecular mass FGF-2 and FGF-2-interacting protein FIF. This opens the possibility of their participation in the regulation of apoptosis.
  • It was shown that while the majority of human leukemia and lymphoma cell lines synthesizes low molecular mass FGF-2, its release is generally insufficient. However, several cell lines display prerequisites to respond to the extracellular FGF-2 that could be produced by other cell types. Importantly, in a majority of cell lines was found concomitant expression of two potent antiapoptotic molecules, high molecular mass FGF-2 and FGF-2-interacting protein FIF. This opens the possibility of their participation in the regulation of apoptosis. (en)
Title
  • FGF-2 expression and its action in human leukemia and lymphoma cell lines.
  • FGF-2 expression and its action in human leukemia and lymphoma cell lines. (en)
skos:prefLabel
  • FGF-2 expression and its action in human leukemia and lymphoma cell lines.
  • FGF-2 expression and its action in human leukemia and lymphoma cell lines. (en)
skos:notation
  • RIV/68378041:_____/03:19033057!RIV/2004/AV0/A19004/N
http://linked.open.../vavai/riv/strany
  • 818;820
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  • P(LN00A065), P(ME 198), Z(AV0Z5039906), Z(MSM 432100001)
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  • N/A
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  • 607213
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  • RIV/68378041:_____/03:19033057
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  • leukemia (en)
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [F94E8100BE05]
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  • Leukemia
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http://linked.open...v/svazekPeriodika
  • 17
http://linked.open...iv/tvurceVysledku
  • Dvořák, Petr
  • Hampl, Aleš
  • Krejčí, P.
  • Laurell, H.
  • Faitová, Jitka
http://linked.open...n/vavai/riv/zamer
issn
  • 0887-6924
number of pages
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