About: Early cycling-independent changes to p27, cyclin D2, and cyclin D3 in differentiating mouse embryonal carcinoma cells.

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About: Early cycling-independent changes to p27, cyclin D2, and cyclin D3 in differentiating mouse embryonal carcinoma cells. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	This study investigates how the amount of the inhibitor of cyclin-dependent kinases p27 relates to the transition from nondifferentiated to differentiated status in pluripotent cells of embryonal origin. It demonstrates that the amounts of p27 and D-type cyclins themselves cannot determine the presence or absence of the pluripotent phenotype of embryonal carcinoma cells, and that coregulation of their quantities may serve some specific differentiation-associated function. This study investigates how the amount of the inhibitor of cyclin-dependent kinases p27 relates to the transition from nondifferentiated to differentiated status in pluripotent cells of embryonal origin. It demonstrates that the amounts of p27 and D-type cyclins themselves cannot determine the presence or absence of the pluripotent phenotype of embryonal carcinoma cells, and that coregulation of their quantities may serve some specific differentiation-associated function. (en)
Title	Early cycling-independent changes to p27, cyclin D2, and cyclin D3 in differentiating mouse embryonal carcinoma cells. Early cycling-independent changes to p27, cyclin D2, and cyclin D3 in differentiating mouse embryonal carcinoma cells. (en)
skos:prefLabel	Early cycling-independent changes to p27, cyclin D2, and cyclin D3 in differentiating mouse embryonal carcinoma cells. Early cycling-independent changes to p27, cyclin D2, and cyclin D3 in differentiating mouse embryonal carcinoma cells. (en)
skos:notation	RIV/68378041:_____/02:19023037!RIV/2003/GA0/A19003/N
http://linked.open.../vavai/riv/strany	421;430
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA204/01/0905), Z(AV0Z5039906)
http://linked.open...iv/cisloPeriodika	N/A
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Hampl, Aleš Bryja, Vítězslav Dvořák, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	643952
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/02:19023037
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	differentiation (en)
http://linked.open.../riv/klicoveSlovo	differentiation
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[808F726CBBBC]
http://linked.open...i/riv/nazevZdroje	Cell Growth&Differentiation
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Interactions and functions of cell cycle regulators in cell differentiation
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	13
http://linked.open...iv/tvurceVysledku	Bryja, Vítězslav Dvořák, Petr Hampl, Aleš Krejčí, P. Pacherník, J. Preclíková, H.
http://linked.open...n/vavai/riv/zamer	The molecular and cellular basis of selected human diseases, mechanisms of normal and pathological function, principles of diagnosis and therapy
issn	1044-9523
number of pages	10 (xsd:int)

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