About: Prespliceosomal Assembly on Micoinjected Precursor mRNA Takes Place in Nuclear Speckles.

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About: Prespliceosomal Assembly on Micoinjected Precursor mRNA Takes Place in Nuclear Speckles. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We show that, in HeLa cells, the (pre)spliceosomal assembly on precursor mRNA (pre-mRNA) is associated with the speckles. We conclude that the (pre)spliceosomal complexs on microinjected pre-mRNA are formed inside the speckles. Their targeting into and accumulation in the speckles is a result of the cumulative loading of splicing factors to the pre-mRNA and the complexes formed give rise to the speckled pattern observed. We show that, in HeLa cells, the (pre)spliceosomal assembly on precursor mRNA (pre-mRNA) is associated with the speckles. We conclude that the (pre)spliceosomal complexs on microinjected pre-mRNA are formed inside the speckles. Their targeting into and accumulation in the speckles is a result of the cumulative loading of splicing factors to the pre-mRNA and the complexes formed give rise to the speckled pattern observed. (en)
Title	Prespliceosomal Assembly on Micoinjected Precursor mRNA Takes Place in Nuclear Speckles. Prespliceosomal Assembly on Micoinjected Precursor mRNA Takes Place in Nuclear Speckles. (en)
skos:prefLabel	Prespliceosomal Assembly on Micoinjected Precursor mRNA Takes Place in Nuclear Speckles. Prespliceosomal Assembly on Micoinjected Precursor mRNA Takes Place in Nuclear Speckles. (en)
skos:notation	RIV/68378041:_____/01:19010011!RIV/2003/AV0/A19003/N
http://linked.open.../vavai/riv/strany	393;406
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA302/99/0587), P(GA304/00/1481), P(VS96129), Z(AV0Z5039906)
http://linked.open...iv/cisloPeriodika	N/A
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Kopský, Vojtěch Večeřová, Jaromíra Melčáková, Štěpánka Raška, Ivan Melčák, Ivo
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	692604
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/01:19010011
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	splicing nuclear speckles (en)
http://linked.open.../riv/klicoveSlovo	splicing nuclear speckles
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[1F0BBDBF58CF]
http://linked.open...i/riv/nazevZdroje	Molecular Biology of the Cell
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Functional organization of the cell nucleus Dynamic structure and function in the cell nucleus Laboratory of gene expression
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	12
http://linked.open...iv/tvurceVysledku	Raška, Ivan Melčáková, Štěpánka Kopský, Vojtěch Večeřová, Jaromíra Melčák, Ivo
http://linked.open...n/vavai/riv/zamer	The molecular and cellular basis of selected human diseases, mechanisms of normal and pathological function, principles of diagnosis and therapy
issn	1059-1524
number of pages	14 (xsd:int)

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