About: Cyclin a down - regulation in TGFb1 - arrested follicular lymphoma cells.

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Cyclin a down - regulation in TGFb1 - arrested follicular lymphoma cells. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We found that the expression of cyclin A and p21 waf1 molecules was primarily modulated by TGFb1 treatment while the expression of other regulatory components, like cyclins D, cyclin E, cdk2, cdk4, and cdk6 or p15 ink4b, p16ink4a, and p27kip1 was not significantly affected. The binding activity of CREB - 1 and ATF - 2 to the CRE region of the cyclin A promoter was almost completely abolished due to the treatment. Moreover, CREB-1 was dephosphorylated due to the treatment as revealed by immunoblotting. We found that the expression of cyclin A and p21 waf1 molecules was primarily modulated by TGFb1 treatment while the expression of other regulatory components, like cyclins D, cyclin E, cdk2, cdk4, and cdk6 or p15 ink4b, p16ink4a, and p27kip1 was not significantly affected. The binding activity of CREB - 1 and ATF - 2 to the CRE region of the cyclin A promoter was almost completely abolished due to the treatment. Moreover, CREB-1 was dephosphorylated due to the treatment as revealed by immunoblotting. (en)
Title	Cyclin a down - regulation in TGFb1 - arrested follicular lymphoma cells. Cyclin a down - regulation in TGFb1 - arrested follicular lymphoma cells. (en)
skos:prefLabel	Cyclin a down - regulation in TGFb1 - arrested follicular lymphoma cells. Cyclin a down - regulation in TGFb1 - arrested follicular lymphoma cells. (en)
skos:notation	RIV/68378041:_____/00:19003071!RIV/2003/AV0/A19003/N
http://linked.open.../vavai/riv/strany	250;259
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA304/00/1481), Z(AV0Z5039906)
http://linked.open...iv/cisloPeriodika	N/A
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Müller, Julius Djaborkhel, Rashed Raška, Ivan Tvrdík, Daniel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	707861
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/00:19003071
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	N/A (en)
http://linked.open.../riv/klicoveSlovo	N/A
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[6D3850A2DFE5]
http://linked.open...i/riv/nazevZdroje	Experimental Cell Research
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Dynamic structure and function in the cell nucleus
http://linked.open...UplatneniVysledku	2000
http://linked.open...v/svazekPeriodika	261
http://linked.open...iv/tvurceVysledku	Eckschlager, T. Raška, Ivan Tvrdík, Daniel Müller, Julius Djaborkhel, Rashed
http://linked.open...n/vavai/riv/zamer	The molecular and cellular basis of selected human diseases, mechanisms of normal and pathological function, principles of diagnosis and therapy
issn	0014-4827
number of pages	10 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software