About: Intra-observer error of mouse long bone cross section digitization

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Digitization of periosteal and endosteal contours of bone cross section is one of several methods used for calculating long bone cross-sectional geometry (CSG). In this study, invasively obtained bone histological samples were used to calculate intra-observer measurement error for CSG parameters. Intra-observer error was measured based upon repeated measurements of cross-sectional areas (total area [TA], cortical area [CA]) and moments of area (I-max, I-min, I-max/I-min, J) in B6CBA mice (n = 17). Cross sections were cut at 50 % of the biomechanical length of the left tibia and the samples were further processed for CSG and histological analysis. Intra-observer error was measured to estimate the accuracy of the digitization method. Accuracy of the tested digitization method was expressed by mean difference (MD), mean absolute difference (MAD), and limits of agreement (LA). The results confirm our assumption that intra-observer error decreases with the number of repeated measurement events. Thus, the error can be minimized by acquiring experience in the section digitizing. Our results also show that TA, CA and polar moment of area (J) are more susceptible to intra-observer error than are I-max, I-min and I-max/I-min. Digitization of periosteal and endosteal contours of bone cross section is one of several methods used for calculating long bone cross-sectional geometry (CSG). In this study, invasively obtained bone histological samples were used to calculate intra-observer measurement error for CSG parameters. Intra-observer error was measured based upon repeated measurements of cross-sectional areas (total area [TA], cortical area [CA]) and moments of area (I-max, I-min, I-max/I-min, J) in B6CBA mice (n = 17). Cross sections were cut at 50 % of the biomechanical length of the left tibia and the samples were further processed for CSG and histological analysis. Intra-observer error was measured to estimate the accuracy of the digitization method. Accuracy of the tested digitization method was expressed by mean difference (MD), mean absolute difference (MAD), and limits of agreement (LA). The results confirm our assumption that intra-observer error decreases with the number of repeated measurement events. Thus, the error can be minimized by acquiring experience in the section digitizing. Our results also show that TA, CA and polar moment of area (J) are more susceptible to intra-observer error than are I-max, I-min and I-max/I-min. (en)
Title	Intra-observer error of mouse long bone cross section digitization Intra-observer error of mouse long bone cross section digitization (en)
skos:prefLabel	Intra-observer error of mouse long bone cross section digitization Intra-observer error of mouse long bone cross section digitization (en)
skos:notation	RIV/68081766:_____/12:00390442!RIV13-GA0-68081766
http://linked.open...avai/riv/aktivita	I P S
http://linked.open...avai/riv/aktivity	I, P(GA206/09/0589), S
http://linked.open...iv/cisloPeriodika	3-4
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Sládek, Vladimír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav biologie obratlovců AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	142758
http://linked.open...ai/riv/idVysledku	RIV/68081766:_____/12:00390442
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	accuracy; cortical bone; CSG; digitization; tibia (en)
http://linked.open.../riv/klicoveSlovo	cortical bone CSG digitization accuracy tibia
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[643AAB5F0242]
http://linked.open...i/riv/nazevZdroje	Folia zoologica
http://linked.open...in/vavai/riv/obor	EG
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	The diachronic changes of long bone cross-sectional geometry in human prehistoric populations in Central Europe: The biomechanical analysis
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	61
http://linked.open...iv/tvurceVysledku	Sládek, Vladimír Jindrová, A. Tůma, J.
http://linked.open...ain/vavai/riv/wos	000313606500015
issn	0139-7893
number of pages	10 (xsd:int)

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