| Attributes | Values |
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| rdf:type
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| Description
| - V práci jsme sledovali, zda jsou MHC geny podrobeny selekci v průběhu populačního cyklu u hryzce vodního. V období nízké populační hustoty, kdy byly jednotlivé populace geograficky izolované, byly jak celková genetická diferenciace, tak i izolace vzáleností více signifikantně více zřetelné na MHC genech než na neutrálních znacích. Zároveň bylo prokázáno, že gen DQA1 je výrazně odlišný (%22outlier%22) zejména v jedné populaci, což naznačuje působení lokální selekce. Tyto rozdíly mezi MHC a neutrálními znaky se postupně vytrácely s rostoucí hustotou. V roce vrcholové hustoty dokonce DQA1 gen vykazoval nižší diferenciaci než neutrální znaky. Jako možný mechanismus pozorovaných změn navrhujeme prostorové a časové změny v parazitárním tlaku a lokus-specifickou selekci. (cs)
- We investigated whether two MHC class II genes (DQA1, DRB) were subjected to contemporary selection during increases in the density of fossorial water vole (Arvicola terrestris) populations. In the low-abundance phase, when populations were geographically isolated, both overall differentiation and isolation-by-distance were more marked for MHC genes than for neutral markers. Model-based simulations identified DQA1 as an outlier (i.e. under selection) in a single population, suggesting the action of local selection in fragmented populations. The differences between MHC and neutral markers gradually disappeared with increasing effective migration between sites. In the high-abundance year, DQA1 displayed significantly lower levels of overall differentiation than the neutral markers. Spatial and temporal fluctuations in parasite pressure and locus-specific selection are probably the most plausible mechanisms underlying the observed changes in selection pattern during the demographic cycle.
- We investigated whether two MHC class II genes (DQA1, DRB) were subjected to contemporary selection during increases in the density of fossorial water vole (Arvicola terrestris) populations. In the low-abundance phase, when populations were geographically isolated, both overall differentiation and isolation-by-distance were more marked for MHC genes than for neutral markers. Model-based simulations identified DQA1 as an outlier (i.e. under selection) in a single population, suggesting the action of local selection in fragmented populations. The differences between MHC and neutral markers gradually disappeared with increasing effective migration between sites. In the high-abundance year, DQA1 displayed significantly lower levels of overall differentiation than the neutral markers. Spatial and temporal fluctuations in parasite pressure and locus-specific selection are probably the most plausible mechanisms underlying the observed changes in selection pattern during the demographic cycle. (en)
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| Title
| - Density-related changes in selection pattern for major histocompatibility complex genes in fluctuating populations of voles
- Typ selekce působící na geny hlavního histokompatibilního systému u hrabošů závisí na hustotě (cs)
- Density-related changes in selection pattern for major histocompatibility complex genes in fluctuating populations of voles (en)
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| skos:prefLabel
| - Density-related changes in selection pattern for major histocompatibility complex genes in fluctuating populations of voles
- Typ selekce působící na geny hlavního histokompatibilního systému u hrabošů závisí na hustotě (cs)
- Density-related changes in selection pattern for major histocompatibility complex genes in fluctuating populations of voles (en)
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| skos:notation
| - RIV/68081766:_____/07:00090913!RIV08-AV0-68081766
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
| - P(IAA600930608), R, Z(AV0Z60930519)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/68081766:_____/07:00090913
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| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - Arvicola terrestris; balancing selection; local adaptation; MHC; population cycles (en)
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| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| |
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Bryja, Josef
- Cosson, J.-F.
- Charbonnel, N.
- Galan, M.
- Berthier, K.
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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