About: Novel flavivirus or new lineage of West Nile Virus, central Europe     Goto   Sponge   NotDistinct   Permalink

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  • A flavivirus (strain 97-103) was isolated from Culex pipens mosquitoes in 1997 following floods in South Moravia, Czech Republic. The strain exhibited close antigenic relationship to West Nile virus (WNV) prototype strain Eg-101 in a cross-neutralization test. In this study, mouse pathogenicity characteristics and the complete nucleotide and putative amino acid sequences of isolate 97-103, named Rabensburg virus (RabV) after a nearby Austrian city, were determined. RabV shares only 75%-77% nucleotide identity and 89%-90% amino acid identity with representative strains of WNV lineages 1 and 2. Another RabV strain (99-222) was isolated in the same location two years later; it showed >99% nucleotide identity to strain 97-103. Phylogenetic analyses of RabV, WNV strains, and other members of the Japanese encephalitis virus (JEV) complex clearly demonstrated that RabV is either a new (third) lineage of WNV or a novel flavivirus of the JEV group.
  • A flavivirus (strain 97-103) was isolated from Culex pipens mosquitoes in 1997 following floods in South Moravia, Czech Republic. The strain exhibited close antigenic relationship to West Nile virus (WNV) prototype strain Eg-101 in a cross-neutralization test. In this study, mouse pathogenicity characteristics and the complete nucleotide and putative amino acid sequences of isolate 97-103, named Rabensburg virus (RabV) after a nearby Austrian city, were determined. RabV shares only 75%-77% nucleotide identity and 89%-90% amino acid identity with representative strains of WNV lineages 1 and 2. Another RabV strain (99-222) was isolated in the same location two years later; it showed >99% nucleotide identity to strain 97-103. Phylogenetic analyses of RabV, WNV strains, and other members of the Japanese encephalitis virus (JEV) complex clearly demonstrated that RabV is either a new (third) lineage of WNV or a novel flavivirus of the JEV group. (en)
  • Po záplavách na jižní Moravě roku 1997 byl z komárů Culex pipiens izolován flavivirus (kmen 97-103), který vykazoval značnou antigenní podobnost s prototypovým kmenem Eg-101 viru West Nile (WNV) ve zkříženém neutralizačním testu. V této práci je charakterizována patogenita tohoto kmene pro myš, a podána uplná sekvence jeho nukleotidů i aminokyselin. Kmen byl pojmenován Rabensburg (RabV) podle nejbližší lokality. RabV má 75%-77% podobnost nukleotidů a 89%-90% podobnost aminokyselin při srovnání s reprezentativními kmeny WNV genomických linií 1 a 2. Další kmen RabV (99-222) byl izolován na stejném místě o 2 roky později, a shoda jeho nukleotidů s kmenem 97-103 byla >99%. Fylogenetický rozbor kmenů RabV, WNV a dalších členů skupiny Japonské encefalitidy (JE) ukázal, že RabV je buď novou (třetí) genomickou linií WNV anebo novým flavivirem skupiny JE. (cs)
Title
  • Novel flavivirus or new lineage of West Nile Virus, central Europe
  • Nový flavivirus nebo nová linie viru West Nile ve střední Evropě (cs)
  • Novel flavivirus or new lineage of West Nile Virus, central Europe (en)
skos:prefLabel
  • Novel flavivirus or new lineage of West Nile Virus, central Europe
  • Nový flavivirus nebo nová linie viru West Nile ve střední Evropě (cs)
  • Novel flavivirus or new lineage of West Nile Virus, central Europe (en)
skos:notation
  • RIV/68081766:_____/05:00023220!RIV06-AV0-68081766
http://linked.open.../vavai/riv/strany
  • 225;231
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA206/03/0726), Z(AV0Z60930519)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 533337
http://linked.open...ai/riv/idVysledku
  • RIV/68081766:_____/05:00023220
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • epidemiology; West Nile virus; Central Europe (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [508B984BB0BB]
http://linked.open...i/riv/nazevZdroje
  • Emerging Infectious Diseases
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 11
http://linked.open...iv/tvurceVysledku
  • Hubálek, Zdeněk
  • Rudolf, Ivo
  • Nowotny, N.
  • Bakonyi, T.
http://linked.open...n/vavai/riv/zamer
issn
  • 1080-6040
number of pages
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