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  • Gen hybridní sterility (Hst1) byl původně popsán u samčího potomstva získaného křížením laboratorních inbredních kmenů myší C57BL/10 a C3H a volně žijících myší Mus musculus musculus, získaných na lokalitách v Praze. Studie si klade otázku, jestli výskyt sterility spojený s genem Hst1 je omezen na místní populaci nebo je rozšířen do geograficky vzdálených regionů. Studovali jsme potomstvo odvozené od volně žijící populace M. m. musculus ze Studence, 160 km jihovýchodně od Prahy, křížené s myší C57BL/10. Spermatogeneze byla vyšetřována u 251 hybridních samců; z nich 109 samců (43,4%) bylo sterilních a 142 (56,6%) bylo fertilních. Molekulární analýza odhalila nedokonalou segregaci sterility a fertility u mužského potomstva a markry Hst1 oblasti u některých rodin. Pravděpodobně tedy existují další geny ovlivňující hybridní sterilitu, které jsou polymorfní u volně žijící M. m. musculus. (cs)
  • The hybrid sterility 1 (Hst1) gene was originally described in male progeny obtained from a cross between laboratory inbred mouse strains C57BL/10 and C3H, and wild Mus musculus musculus, sampled at localities in Prague, Czech Republic. This study asked whether the presence of sterility associated with the Hst1 gene is limited to one local population or is extended over geographically distant regions. We studied the progeny derived from a wild population of M. m. musculus sampled in Studenec, Czech Republic, 160 km south-east from Prague, crossed to C57BL/10 mice. Spermatogenesis was examined in 251 hybrid males; among them 109 males (43.4%) were sterile and 142 (56.6%) were fertile. Molecular analysis revealed incomplete segregation of sterility and fertility in male progeny and markers from the Hst1 region in some families. Therefore, there are probably additional genes affecting hybrid sterility that are polymorphic in wild M. m. musculus.
  • The hybrid sterility 1 (Hst1) gene was originally described in male progeny obtained from a cross between laboratory inbred mouse strains C57BL/10 and C3H, and wild Mus musculus musculus, sampled at localities in Prague, Czech Republic. This study asked whether the presence of sterility associated with the Hst1 gene is limited to one local population or is extended over geographically distant regions. We studied the progeny derived from a wild population of M. m. musculus sampled in Studenec, Czech Republic, 160 km south-east from Prague, crossed to C57BL/10 mice. Spermatogenesis was examined in 251 hybrid males; among them 109 males (43.4%) were sterile and 142 (56.6%) were fertile. Molecular analysis revealed incomplete segregation of sterility and fertility in male progeny and markers from the Hst1 region in some families. Therefore, there are probably additional genes affecting hybrid sterility that are polymorphic in wild M. m. musculus. (en)
Title
  • Does geography matter in hybrid sterility in house mice?
  • Does geography matter in hybrid sterility in house mice? (en)
  • Ovlivňuje geografie hybridní sterilitu domácí myši? (cs)
skos:prefLabel
  • Does geography matter in hybrid sterility in house mice?
  • Does geography matter in hybrid sterility in house mice? (en)
  • Ovlivňuje geografie hybridní sterilitu domácí myši? (cs)
skos:notation
  • RIV/68081766:_____/05:00000349!RIV/2005/GA0/A67005/N
http://linked.open.../vavai/riv/strany
  • 663;674
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GV204/98/K015), P(IAA6045601), Z(AV0Z6093917)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 518545
http://linked.open...ai/riv/idVysledku
  • RIV/68081766:_____/05:00000349
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • inbred strain;Mus musculus;spermatogenesis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [E10CE267A838]
http://linked.open...i/riv/nazevZdroje
  • Biological Journal of the Linnean Society
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 84
http://linked.open...iv/tvurceVysledku
  • Forejt, Jiří
  • Piálek, Jaroslav
  • Vyskočilová, Martina
  • Trachtulec, Zdeněk
http://linked.open...n/vavai/riv/zamer
issn
  • 0024-4066
number of pages
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