About: Stereotactic radiofrequency amygdalohippocampectomy for the treatment of temporal lobe epilepsy: Do good neuropsychological and seizure outcomes correlate with hippocampal volume reduction?     Goto   Sponge   NotDistinct   Permalink

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  • Temporal lobe surgery bears the risk of a decline of neuropsychological functions. Stereotactic radiofrequency amygdalohippocampectomy (SAHE) represents an alternative to mesial temporal lobe epilepsy (MTLE) surgery. This study compared neuropsychological results with MRI volumetry of the residual hippocampus. We included 35 patients with drug-resistant MTLE treated by SAHE. MRI volumetry and neuropsychological examinations were performed before and 1 year after SAHE. One year after SAHE 77% of patients were assessed as Engel Class I, 14% of patients was classified as Engel II and in 9% of patients treatment failed. Two years after SAHE 76% of subjects were classified as Engel Class I, 15% of patients was assessed as Engel II and in 9% of patients treatment failed. One year after SAHE, intelligence quotients of treated patients increased. Patients showed significant improvement in verbal memory (p = 0.039) and the semantic long-term memory subtest (LTM) (p = 0.003).
  • Temporal lobe surgery bears the risk of a decline of neuropsychological functions. Stereotactic radiofrequency amygdalohippocampectomy (SAHE) represents an alternative to mesial temporal lobe epilepsy (MTLE) surgery. This study compared neuropsychological results with MRI volumetry of the residual hippocampus. We included 35 patients with drug-resistant MTLE treated by SAHE. MRI volumetry and neuropsychological examinations were performed before and 1 year after SAHE. One year after SAHE 77% of patients were assessed as Engel Class I, 14% of patients was classified as Engel II and in 9% of patients treatment failed. Two years after SAHE 76% of subjects were classified as Engel Class I, 15% of patients was assessed as Engel II and in 9% of patients treatment failed. One year after SAHE, intelligence quotients of treated patients increased. Patients showed significant improvement in verbal memory (p = 0.039) and the semantic long-term memory subtest (LTM) (p = 0.003). (en)
Title
  • Stereotactic radiofrequency amygdalohippocampectomy for the treatment of temporal lobe epilepsy: Do good neuropsychological and seizure outcomes correlate with hippocampal volume reduction?
  • Stereotactic radiofrequency amygdalohippocampectomy for the treatment of temporal lobe epilepsy: Do good neuropsychological and seizure outcomes correlate with hippocampal volume reduction? (en)
skos:prefLabel
  • Stereotactic radiofrequency amygdalohippocampectomy for the treatment of temporal lobe epilepsy: Do good neuropsychological and seizure outcomes correlate with hippocampal volume reduction?
  • Stereotactic radiofrequency amygdalohippocampectomy for the treatment of temporal lobe epilepsy: Do good neuropsychological and seizure outcomes correlate with hippocampal volume reduction? (en)
skos:notation
  • RIV/68081740:_____/12:00383737!RIV13-AV0-68081740
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, Z(AV0Z70250504)
http://linked.open...iv/cisloPeriodika
  • 1-2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 171402
http://linked.open...ai/riv/idVysledku
  • RIV/68081740:_____/12:00383737
http://linked.open...riv/jazykVysledku
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  • epilepsy; stereotactic surgery; neuropsychological outcome (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [492F0D527F3D]
http://linked.open...i/riv/nazevZdroje
  • Epilepsy Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 102
http://linked.open...iv/tvurceVysledku
  • Lukavský, Jiří
  • Liščák, R.
  • Procházka, T.
  • Druga, R.
  • Krámská, L.
  • Malíková, H.
  • Marečková, I.
  • Vojtěch, Z.
http://linked.open...ain/vavai/riv/wos
  • 000311529400005
http://linked.open...n/vavai/riv/zamer
issn
  • 0920-1211
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.eplepsyres.2012.04.017
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