About: Onset of action of atypical and typical antipsychotics in the treatment of adolescent schizophrenic psychoses

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aim was to assess the time to first improvement associated with atypical (AAP) and typical (TAP) antipsychotic drugs in patients with early-onset schizophrenia. This study involved a chart review of all schizophrenic patients in our hospital, with selected AAPs and TAPs, between 1997 and 2007 (296 teenage patients, 141 males, 155 females; mean age 16 years). The time to first improvement could be estimated in 258 patients; of these, 195 patients treated with AAPs and 63 patients with TAPs. Most patients were taking risperidone (96), followed by olanzapine (64). The mean time to first improvement was 6,9 days in the AAP group and 5,8 days in the TAP group (p=0,063). The mean time to first improvement was 7,1 days for risperidone, 6,7 days for olanzapine, 6,5 for ziprasidone, 6,1 for quetiapine, 7,4 for clozapine, 5,2 for haloperidol, 5,9 for perphenazine, and 6,0 for sulpiride. Differences among drugs were not significant (p=0.680). The aim was to assess the time to first improvement associated with atypical (AAP) and typical (TAP) antipsychotic drugs in patients with early-onset schizophrenia. This study involved a chart review of all schizophrenic patients in our hospital, with selected AAPs and TAPs, between 1997 and 2007 (296 teenage patients, 141 males, 155 females; mean age 16 years). The time to first improvement could be estimated in 258 patients; of these, 195 patients treated with AAPs and 63 patients with TAPs. Most patients were taking risperidone (96), followed by olanzapine (64). The mean time to first improvement was 6,9 days in the AAP group and 5,8 days in the TAP group (p=0,063). The mean time to first improvement was 7,1 days for risperidone, 6,7 days for olanzapine, 6,5 for ziprasidone, 6,1 for quetiapine, 7,4 for clozapine, 5,2 for haloperidol, 5,9 for perphenazine, and 6,0 for sulpiride. Differences among drugs were not significant (p=0.680). (en)
Title	Onset of action of atypical and typical antipsychotics in the treatment of adolescent schizophrenic psychoses Onset of action of atypical and typical antipsychotics in the treatment of adolescent schizophrenic psychoses (en)
skos:prefLabel	Onset of action of atypical and typical antipsychotics in the treatment of adolescent schizophrenic psychoses Onset of action of atypical and typical antipsychotics in the treatment of adolescent schizophrenic psychoses (en)
skos:notation	RIV/68081740:_____/11:00371948!RIV13-AV0-68081740
http://linked.open...avai/riv/aktivita	I Z
http://linked.open...avai/riv/aktivity	I, Z(AV0Z70250504), Z(MSM0021620849)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Urbánek, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Psychologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	218394
http://linked.open...ai/riv/idVysledku	RIV/68081740:_____/11:00371948
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	schizophrenia; antipsychotics; onset of action (en)
http://linked.open.../riv/klicoveSlovo	onset of action schizophrenia antipsychotics
http://linked.open...odStatuVydavatele	SE - Švédské království
http://linked.open...ontrolniKodProRIV	[E491B96D940C]
http://linked.open...i/riv/nazevZdroje	Neuroendocrinology Letters
http://linked.open...in/vavai/riv/obor	AN
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	32
http://linked.open...iv/tvurceVysledku	Urbánek, Tomáš Dudová, I. Hrdlička, M. Zedková, I.
http://linked.open...ain/vavai/riv/wos	000300543900015
http://linked.open...n/vavai/riv/zamer	Člověk v kontextech celoživotního vývoje Neuropsychiatrické aspekty neurodegenerativních onemocnění
issn	0172-780X
number of pages	4 (xsd:int)

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