About: Simulation based design of a microfabricated pneumatic electrospray nebulizer

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A microfabricated pneumatic electrospray nebulizer has been developed and evaluated using computer simulations and experimental measurements of the mass spectrometry signals. The microdevice under development is designed for electrospray mass spectrometry interfacing without the need to fabricate an electrospray needle and can be used as a disposable or an integral part of a reusable system. The design of the chip layout was supported by computational fluid dynamics simulations. The tested microdevices were fabricated in glass using conventional photolithography, followed by wet chemical etching and thermal bonding. The performance of the microfabricated nebulizer was evaluated by means of time-of-flight mass spectrometry with a peptide mixture. It was demonstrated that the nebulizer, operating at supersonic speed of the nebulizing gas, produced very stable nanospray (900 nl/min) as documented by less than 0.1 % (standard error) fluctuation in total mass spectrometric signal intensity. A microfabricated pneumatic electrospray nebulizer has been developed and evaluated using computer simulations and experimental measurements of the mass spectrometry signals. The microdevice under development is designed for electrospray mass spectrometry interfacing without the need to fabricate an electrospray needle and can be used as a disposable or an integral part of a reusable system. The design of the chip layout was supported by computational fluid dynamics simulations. The tested microdevices were fabricated in glass using conventional photolithography, followed by wet chemical etching and thermal bonding. The performance of the microfabricated nebulizer was evaluated by means of time-of-flight mass spectrometry with a peptide mixture. It was demonstrated that the nebulizer, operating at supersonic speed of the nebulizing gas, produced very stable nanospray (900 nl/min) as documented by less than 0.1 % (standard error) fluctuation in total mass spectrometric signal intensity. (en)
Title	Simulation based design of a microfabricated pneumatic electrospray nebulizer Simulation based design of a microfabricated pneumatic electrospray nebulizer (en)
skos:prefLabel	Simulation based design of a microfabricated pneumatic electrospray nebulizer Simulation based design of a microfabricated pneumatic electrospray nebulizer (en)
skos:notation	RIV/68081715:_____/15:00434464!RIV15-GA0-68081715
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GBP206/12/G014)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Foret, František Grym, Jakub
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav analytické chemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	425
http://linked.open...ai/riv/idVysledku	RIV/68081715:_____/15:00434464
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	CFD; microfabrication; modeling; electrospray; nebulizer (en)
http://linked.open.../riv/klicoveSlovo	microfabrication electrospray CFD modeling nebulizer
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[6BB051A34CC1]
http://linked.open...i/riv/nazevZdroje	Electrophoresis
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Center for advanced bioanalytical technologies
http://linked.open...UplatneniVysledku	2015
http://linked.open...v/svazekPeriodika	36
http://linked.open...iv/tvurceVysledku	Foret, František Guttman, A. Grym, Jakub Járvás, G.
http://linked.open...ain/vavai/riv/wos	000349220500003
issn	0173-0835
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1002/elps.201400387

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