About: Quaternary benzo[c]phenanthridine alkaloids biological activities.Intracellular targets of their action and application in human and veterinary medicine.

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About: Quaternary benzo[c]phenanthridine alkaloids biological activities.Intracellular targets of their action and application in human and veterinary medicine. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The article briefly reviewes information on the occurence of of benzo[c]phenanthridine alkaloids (QBA) in plats and on their chemical properties important from the viewpoint of QBA biological and biochemical activities. Than recent results of investigation of authors on QBA are presented: 1. Identification of chemical forms of sanguinarine and cheleryhtrine that complex with mercapto nuclophiles and the determination of stability constants that characterize their binding with human serum albumin;2. Inhibition effects of sanguinarine, cheleryhtrine and fagaronine on DPP-IV-like enzymes isolated from blood plasma and human and rat glinoma cell lines; and 3. QBA role in the genesis of epidemic dropsy syndrome. The article briefly reviewes information on the occurence of of benzo[c]phenanthridine alkaloids (QBA) in plats and on their chemical properties important from the viewpoint of QBA biological and biochemical activities. Than recent results of investigation of authors on QBA are presented: 1. Identification of chemical forms of sanguinarine and cheleryhtrine that complex with mercapto nuclophiles and the determination of stability constants that characterize their binding with human serum albumin;2. Inhibition effects of sanguinarine, cheleryhtrine and fagaronine on DPP-IV-like enzymes isolated from blood plasma and human and rat glinoma cell lines; and 3. QBA role in the genesis of epidemic dropsy syndrome. (en)
Title	Quaternary benzo[c]phenanthridine alkaloids biological activities.Intracellular targets of their action and application in human and veterinary medicine. Quaternary benzo[c]phenanthridine alkaloids biological activities.Intracellular targets of their action and application in human and veterinary medicine. (en)
skos:prefLabel	Quaternary benzo[c]phenanthridine alkaloids biological activities.Intracellular targets of their action and application in human and veterinary medicine. Quaternary benzo[c]phenanthridine alkaloids biological activities.Intracellular targets of their action and application in human and veterinary medicine. (en)
skos:notation	RIV/68081715:_____/03:25033090!RIV/2004/GA0/A25004/N
http://linked.open.../vavai/riv/strany	245;254
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/02/0023), Z(AV0Z4031919)
http://linked.open...vai/riv/dodaniDat	2004
http://linked.open...aciTvurceVysledku	Vespalec, Radim
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav analytické chemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	624432
http://linked.open...ai/riv/idVysledku	RIV/68081715:_____/03:25033090
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	benzo[c]phenanthridine alkaloids; sanguinarine; chelerythrine (en)
http://linked.open.../riv/klicoveSlovo	benzo[c]phenanthridine alkaloids chelerythrine sanguinarine
http://linked.open...ontrolniKodProRIV	[E6AF90BB3BE8]
http://linked.open...i/riv/mistoVydani	Dordrecht
http://linked.open...vEdiceCisloSvazku	(1)
http://linked.open...i/riv/nazevZdroje	Chemical Probes in Biology. Science at the Interface of Chemistry, Biology and Medicine. NATO Science Series, II. Mathematics, Physics and Chemistry, Vol. 129.
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Development of new procedures for highly reliable analytical control of technologies,materials,food &environment & for med. diagnostic using modern instrumentat
http://linked.open...UplatneniVysledku	2003
http://linked.open...iv/tvurceVysledku	Ulrichová, J. Šimánek, V. Šedo, A. Vespalec, Radim Vičar, J.
http://linked.open...n/vavai/riv/zamer	Vyvinutí nových metod analytické chemie pro potřeby společenské praxe
number of pages	9 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Kluwer Academic Publishers
https://schema.org/isbn	1-4020-1769-3

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