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  • Histamine has the ability to influence the activity of immune cells including neutrophils and plays a pivotal role in inflammatory processes, which are a complex network of cellular and humoral events. One of the main functions manifested by activated neutrophils is oxidative burst, which is linked to the production of reactive oxygen species; therefore, the effects of histamine receptor agonists and antagonists on the oxidative burst of neutrophils is reviewed. A role for the well-characterized histamine H-1 and H-2 receptors in this process is discussed and compared to that of the recently discovered H-4 receptor.
  • Histamine has the ability to influence the activity of immune cells including neutrophils and plays a pivotal role in inflammatory processes, which are a complex network of cellular and humoral events. One of the main functions manifested by activated neutrophils is oxidative burst, which is linked to the production of reactive oxygen species; therefore, the effects of histamine receptor agonists and antagonists on the oxidative burst of neutrophils is reviewed. A role for the well-characterized histamine H-1 and H-2 receptors in this process is discussed and compared to that of the recently discovered H-4 receptor. (en)
Title
  • Modulation of neutrophil oxidative burst via histamine receptors
  • Modulation of neutrophil oxidative burst via histamine receptors (en)
skos:prefLabel
  • Modulation of neutrophil oxidative burst via histamine receptors
  • Modulation of neutrophil oxidative burst via histamine receptors (en)
skos:notation
  • RIV/68081707:_____/13:00436837!RIV15-AV0-68081707
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  • I, P(LD11010)
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  • 1
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  • 89251
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  • RIV/68081707:_____/13:00436837
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  • neutrophil; oxidative burst; reactive oxygen species (en)
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [C06C94C2FD60]
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  • British Journal of Pharmacology
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  • 170
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  • Lojek, Antonín
  • Číž, Milan
http://linked.open...ain/vavai/riv/wos
  • 000323131600003
issn
  • 0007-1188
number of pages
http://bibframe.org/vocab/doi
  • 10.1111/bph.12107
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