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rdf:type
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Description
| - We show that the BRCA1 alternative splicing variant D14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in MCF7 cells, especially the non-homologous en-joining (NHEJ). This finding demonstrate possibly pathological potential of BRCA1 splicing variants generated by an altered or misregulated alternative splicing in the processes of mammary malignant transformation.
- We show that the BRCA1 alternative splicing variant D14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in MCF7 cells, especially the non-homologous en-joining (NHEJ). This finding demonstrate possibly pathological potential of BRCA1 splicing variants generated by an altered or misregulated alternative splicing in the processes of mammary malignant transformation. (en)
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Title
| - The BRCA1 alternative splicing variant delta14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in MCF-7 cells
- The BRCA1 alternative splicing variant delta14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in MCF-7 cells (en)
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skos:prefLabel
| - The BRCA1 alternative splicing variant delta14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in MCF-7 cells
- The BRCA1 alternative splicing variant delta14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in MCF-7 cells (en)
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skos:notation
| - RIV/68081707:_____/12:00378624!RIV13-AV0-68081707
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(IAA500040802), P(NT12280), S, Z(AV0Z50040702)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/68081707:_____/12:00378624
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - BRCA1; alternative splicing; DNA repair (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Kozubek, Stanislav
- Lukášová, Emilie
- Weiterová, Lenka
- Ševčík, J.
- Falk, Martin
- Janatová, M.
- Kleibl, Z.
- Kleiblová, P.
- Lhota, F.
- Pohlreich, P.
- Štefančíková, L.
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.cellsig.2011.12.023
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