About: Oxidation of sanguinarine and its dihydro-derivative at a pyrolytic graphite electrode using ex situ voltammetry. Study of the interactions of the alkaloids with DNA     Goto   Sponge   NotDistinct   Permalink

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Description
  • This study describes oxidation of sanguinarine (SG) and its metabolite dihydrosanguinarine (DHSG) on the surface of a basal-plane pyrolytic graphite electrode (PGE). Since both alkaloids strongly adsorb onto the surface of pyrolytic graphite, measurements were performed using ex situ voltammetric methods, adsorptive transfer (AdT) cyclic voltammetry (CV) and square-wave voltammetry (SWV). The electrochemical results and optimized AdT SWV were subsequently applied for study of the interactions of SG and DHSG with DNA in vitro. Electrochemical study of the interactions was supported and complemented with measurements using gel electrophoresis and fluorescence spectroscopy.
  • This study describes oxidation of sanguinarine (SG) and its metabolite dihydrosanguinarine (DHSG) on the surface of a basal-plane pyrolytic graphite electrode (PGE). Since both alkaloids strongly adsorb onto the surface of pyrolytic graphite, measurements were performed using ex situ voltammetric methods, adsorptive transfer (AdT) cyclic voltammetry (CV) and square-wave voltammetry (SWV). The electrochemical results and optimized AdT SWV were subsequently applied for study of the interactions of SG and DHSG with DNA in vitro. Electrochemical study of the interactions was supported and complemented with measurements using gel electrophoresis and fluorescence spectroscopy. (en)
Title
  • Oxidation of sanguinarine and its dihydro-derivative at a pyrolytic graphite electrode using ex situ voltammetry. Study of the interactions of the alkaloids with DNA
  • Oxidation of sanguinarine and its dihydro-derivative at a pyrolytic graphite electrode using ex situ voltammetry. Study of the interactions of the alkaloids with DNA (en)
skos:prefLabel
  • Oxidation of sanguinarine and its dihydro-derivative at a pyrolytic graphite electrode using ex situ voltammetry. Study of the interactions of the alkaloids with DNA
  • Oxidation of sanguinarine and its dihydro-derivative at a pyrolytic graphite electrode using ex situ voltammetry. Study of the interactions of the alkaloids with DNA (en)
skos:notation
  • RIV/68081707:_____/11:00370858!RIV12-AV0-68081707
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GPP503/11/P312), P(LC06035), Z(AV0Z50040507), Z(AV0Z50040702), Z(MSM6198959215), Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika
  • 7
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 219321
http://linked.open...ai/riv/idVysledku
  • RIV/68081707:_____/11:00370858
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • isoquinoline alkaloids; dihydrosanguinarine; voltammetry (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [C159563AB0F0]
http://linked.open...i/riv/nazevZdroje
  • Electroanalysis
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
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http://linked.open...v/svazekPeriodika
  • 23
http://linked.open...iv/tvurceVysledku
  • Fojta, Miroslav
  • Kubala, M.
  • Ulrichová, J.
  • Vacek, J.
  • Šimková, Eva
  • Hrbáč, J.
  • Janovská, M.
  • Skopalová, J.
  • Stýskala, J.
  • Vrublová, E.
http://linked.open...ain/vavai/riv/wos
  • 000292967900021
http://linked.open...n/vavai/riv/zamer
issn
  • 1040-0397
number of pages
http://bibframe.org/vocab/doi
  • 10.1002/elan.201100028
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