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rdf:type
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Description
| - Beta-catenin is a key integrator of cadherin-mediated cell-cell adhesion and transcriptional regulation through the Wnt/beta-catenin pathway, which plays an important role in liver biology. In the present study, we showed that, although beta-catenin may augment the expression of selected target genes of the AhR, a transcriptional factor mediating toxic effects of persistent organic pollutants, the AhR activation may lead to downregulation of Wnt/beta-catenin signaling, and alterations in differentiation and/or proliferative status of liver progenitor cells.
- Beta-catenin is a key integrator of cadherin-mediated cell-cell adhesion and transcriptional regulation through the Wnt/beta-catenin pathway, which plays an important role in liver biology. In the present study, we showed that, although beta-catenin may augment the expression of selected target genes of the AhR, a transcriptional factor mediating toxic effects of persistent organic pollutants, the AhR activation may lead to downregulation of Wnt/beta-catenin signaling, and alterations in differentiation and/or proliferative status of liver progenitor cells. (en)
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Title
| - The interplay of the aryl hydrocarbon receptor and beta-catenin alters both AhR-dependent transcription and Wnt/beta-catenin signaling in liver progenitors
- The interplay of the aryl hydrocarbon receptor and beta-catenin alters both AhR-dependent transcription and Wnt/beta-catenin signaling in liver progenitors (en)
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skos:prefLabel
| - The interplay of the aryl hydrocarbon receptor and beta-catenin alters both AhR-dependent transcription and Wnt/beta-catenin signaling in liver progenitors
- The interplay of the aryl hydrocarbon receptor and beta-catenin alters both AhR-dependent transcription and Wnt/beta-catenin signaling in liver progenitors (en)
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skos:notation
| - RIV/68081707:_____/11:00366424!RIV12-AV0-68081707
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA524/09/1337), P(GD204/09/H058), Z(AV0Z50040507), Z(AV0Z50040702), Z(MSM0021622430), Z(MZE0002716202)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/68081707:_____/11:00366424
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - dioxin; beta-catenin; AhR (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Bryja, Vítězslav
- Kozubík, Alois
- Machala, M.
- Procházková, Jiřina
- Umannová, Lenka
- Vondráček, Jan
- Bernatík, O.
- Kabátková, Markéta
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://bibframe.org/vocab/doi
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