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rdf:type
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Description
| - The organic cation transporters play a more important role in the mechanism of cytotoxicity of JM118 than in the cytotoxicity of cisplatin. Satraplatin is a poor substrate of these transporters. Satraplatin reacts with glutathione with the rate markedly lower than JM118 and cisplatin. Satraplatin can be activated by glutathione allowing it to react with DNA.
- The organic cation transporters play a more important role in the mechanism of cytotoxicity of JM118 than in the cytotoxicity of cisplatin. Satraplatin is a poor substrate of these transporters. Satraplatin reacts with glutathione with the rate markedly lower than JM118 and cisplatin. Satraplatin can be activated by glutathione allowing it to react with DNA. (en)
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Title
| - Studies on cellular accumulation of satraplatin and its major metabolite JM118 and their interactions with glutathione
- Studies on cellular accumulation of satraplatin and its major metabolite JM118 and their interactions with glutathione (en)
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skos:prefLabel
| - Studies on cellular accumulation of satraplatin and its major metabolite JM118 and their interactions with glutathione
- Studies on cellular accumulation of satraplatin and its major metabolite JM118 and their interactions with glutathione (en)
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skos:notation
| - RIV/68081707:_____/10:00353777!RIV11-MSM-68081707
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GAP301/10/0598), P(IAA400040803), P(ME08017), P(ME10066), P(OC08003), Z(AV0Z50040507), Z(AV0Z50040702)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/68081707:_____/10:00353777
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - JM118; cellular accumulation; glutathione (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Brabec, Viktor
- Kostrhunová, Hana
- Kašpárková, Jana
- Gibson, D.
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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