About: Determination of the level of DNA modification with cisplatin by catalytic hydrogen evolution at mercury-based electrodes

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About: Determination of the level of DNA modification with cisplatin by catalytic hydrogen evolution at mercury-based electrodes Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this paper we used voltammetry at the mercury-based electrodes for the monitoring of DNA modification with cisdiamminedichloroplatinum (cisplatin), a representative of metallodrugs used in the treatment of various types of cancer or being developed for such purpose. Application of the electrochemical technique in studies of DNA reactivity with various anticancer platinum compounds, as well as for an easy determination of the extent of DNA platination in studies of its biochemical effects, is discussed. In this paper we used voltammetry at the mercury-based electrodes for the monitoring of DNA modification with cisdiamminedichloroplatinum (cisplatin), a representative of metallodrugs used in the treatment of various types of cancer or being developed for such purpose. Application of the electrochemical technique in studies of DNA reactivity with various anticancer platinum compounds, as well as for an easy determination of the extent of DNA platination in studies of its biochemical effects, is discussed. (en)
Title	Determination of the level of DNA modification with cisplatin by catalytic hydrogen evolution at mercury-based electrodes Determination of the level of DNA modification with cisplatin by catalytic hydrogen evolution at mercury-based electrodes (en)
skos:prefLabel	Determination of the level of DNA modification with cisplatin by catalytic hydrogen evolution at mercury-based electrodes Determination of the level of DNA modification with cisplatin by catalytic hydrogen evolution at mercury-based electrodes (en)
skos:notation	RIV/68081707:_____/10:00342607!RIV11-MSM-68081707
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1QS500040581), P(GP204/07/P476), P(IAA500040701), P(LC06035), Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Vidláková, Pavlína Těsnohlídková, Lucie Havran, Luděk Fojta, Miroslav Horáková, Petra Pivoňková, Hana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	253822
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/10:00342607
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cisplatin; electrochemical analysis of DNA; mercury electrode (en)
http://linked.open.../riv/klicoveSlovo	cisplatin mercury electrode electrochemical analysis of DNA
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[1EC739F84199]
http://linked.open...i/riv/nazevZdroje	Analytical Chemistry
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Metallodrugs, design and mechansim of action Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine. Interactions of p73 protein and its isoforms with DNA. Influences of DNA supercoiling, conformation and anticancer drugs Interactions of wild type and mutant p53 proteins with damaged DNA and their roles in cellular response to anticancer chemotherapy
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	82
http://linked.open...iv/tvurceVysledku	Fojta, Miroslav Havran, Luděk Horáková, Petra Vidláková, Pavlína Pivoňková, Hana Těsnohlídková, Lucie
http://linked.open...ain/vavai/riv/wos	000276004000051
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions
issn	0003-2700
number of pages	8 (xsd:int)

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