About: Inhibition of canonical Wnt signaling promotes gliogenesis in PO-NSCs

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Writ signaling plays an essential role in the development of mammalian central nervous system. We investigated the impact of activation/inhibition of the Writ signaling pathway on neuronal/glial differentiation in neurospheres derived from neonatal mouse forebrains. For short term alterations, neurospheres were stimulated with recombinant Wnt-3a, Wnt-5a and the Wnt inhibitor Dickkopf-1 (Dkk1). Writ signaling plays an essential role in the development of mammalian central nervous system. We investigated the impact of activation/inhibition of the Writ signaling pathway on neuronal/glial differentiation in neurospheres derived from neonatal mouse forebrains. For short term alterations, neurospheres were stimulated with recombinant Wnt-3a, Wnt-5a and the Wnt inhibitor Dickkopf-1 (Dkk1). (en)
Title	Inhibition of canonical Wnt signaling promotes gliogenesis in PO-NSCs Inhibition of canonical Wnt signaling promotes gliogenesis in PO-NSCs (en)
skos:prefLabel	Inhibition of canonical Wnt signaling promotes gliogenesis in PO-NSCs Inhibition of canonical Wnt signaling promotes gliogenesis in PO-NSCs (en)
skos:notation	RIV/68081707:_____/09:00345341!RIV11-AV0-68081707
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z50040507), Z(AV0Z50040702), Z(MSM0021622430)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Bryja, Vítězslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	319545
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/09:00345341
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	differentiation; gliogenesis; neuronal progenitor cells (en)
http://linked.open.../riv/klicoveSlovo	gliogenesis neuronal progenitor cells differentiation
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[1FCACC374A1D]
http://linked.open...i/riv/nazevZdroje	Biochemical and Biophysical Research Communications
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	386
http://linked.open...iv/tvurceVysledku	Bryja, Vítězslav Krauss, S. Arenas, E. Kunke, D. Mygland, L.
http://linked.open...ain/vavai/riv/wos	000268462100016
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies
issn	0006-291X
number of pages	6 (xsd:int)

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