About: Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells     Goto   Sponge   NotDistinct   Permalink

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  • We have investigated the efficiency of a combined modality approach employing 24 h pretreatment of relatively PDT-resistant HT-29 colon adenocarcinoma cells with proadifen followed by HY-PDT. Since significant accumulation of hypericin was found to be a principal factor responsible for ROS induction and therefore higher efficiency of HY-PDT, involvement of ABC transporter system was evaluated.
  • We have investigated the efficiency of a combined modality approach employing 24 h pretreatment of relatively PDT-resistant HT-29 colon adenocarcinoma cells with proadifen followed by HY-PDT. Since significant accumulation of hypericin was found to be a principal factor responsible for ROS induction and therefore higher efficiency of HY-PDT, involvement of ABC transporter system was evaluated. (en)
Title
  • Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells
  • Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells (en)
skos:prefLabel
  • Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells
  • Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells (en)
skos:notation
  • RIV/68081707:_____/09:00340647!RIV10-AV0-68081707
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V, Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika
  • 12
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 311406
http://linked.open...ai/riv/idVysledku
  • RIV/68081707:_____/09:00340647
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • hypericin; photodynamic therapy; ABC transporters (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [001CD0DE93D4]
http://linked.open...i/riv/nazevZdroje
  • Photochemical & Photobiological Sciences
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
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  • 8
http://linked.open...iv/tvurceVysledku
  • Hofmanová, Jiřina
  • Kozubík, Alois
  • Procházková, Jiřina
  • Souček, Karel
  • Fedoročko, P.
  • Jendželovský, R.
  • Koval, J.
  • Mikeš, J.
  • Sačková, V.
  • Kello, M.
http://linked.open...ain/vavai/riv/wos
  • 000272142300010
http://linked.open...n/vavai/riv/zamer
issn
  • 1474-905X
number of pages
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