About: Sensitive voltammetric detection of DNA damage at carbon electrodes using DNA repair enzymes and an electroactive osmium marker

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About: Sensitive voltammetric detection of DNA damage at carbon electrodes using DNA repair enzymes and an electroactive osmium marker Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A new approach was proposed to electrochemical sensing of DNA damage, using osmium DNA markers and voltammetric detection at the pyrolytic graphite electrode. The technique is based on enzymatic digestion of DNA with a DNA repair enzyme exonuclease III, followed by single-strand selective DNA modification by a complex of osmium tetroxide with 2,2'-bipyridine. A new approach was proposed to electrochemical sensing of DNA damage, using osmium DNA markers and voltammetric detection at the pyrolytic graphite electrode. The technique is based on enzymatic digestion of DNA with a DNA repair enzyme exonuclease III, followed by single-strand selective DNA modification by a complex of osmium tetroxide with 2,2'-bipyridine. (en) Nový přístup k elektrochemické detekci poškození DNA používající osmiovou DNA značku a voltametrické stanovení na elektrodě z pyrolytického grafitu. Technika je založena na enzymatickém štěpení DNA DNA-reparačním enzymem exonukleázou III, které je následováno modifikací DNA komplexem oxidu osmičelého s 2,2'-bipyridinem, která je selektivní pro jednořetězcovou DNA. (cs)
Title	Sensitive voltammetric detection of DNA damage at carbon electrodes using DNA repair enzymes and an electroactive osmium marker Sensitive voltammetric detection of DNA damage at carbon electrodes using DNA repair enzymes and an electroactive osmium marker (en) Citlivá detekce poškození DNA na uhlíkových elektrodách za použití DNA reparačních enzymů a elektroaktivní osmiové značky (cs)
skos:prefLabel	Sensitive voltammetric detection of DNA damage at carbon electrodes using DNA repair enzymes and an electroactive osmium marker Sensitive voltammetric detection of DNA damage at carbon electrodes using DNA repair enzymes and an electroactive osmium marker (en) Citlivá detekce poškození DNA na uhlíkových elektrodách za použití DNA reparačních enzymů a elektroaktivní osmiové značky (cs)
skos:notation	RIV/68081707:_____/08:00311428!RIV09-AV0-68081707
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/07/1195), P(IAA400040611), P(IAA4004402), P(LC06035), Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Cahová, Kateřina Vacek, Jan Havran, Luděk Fojta, Miroslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	394388
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/08:00311428
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	DNA damage; electroactive marker; carbon electrodes (en)
http://linked.open.../riv/klicoveSlovo	DNA damage carbon electrodes electroactive marker
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[8D7956B0DB35]
http://linked.open...i/riv/nazevZdroje	Analytical and Bioanalytical Chemistry
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine. Analysis of DNA structure and interactions using electrochemical techniques and chemical probes. Novel techniques and sensors for DNA damage detection Application of electrochemical methods in studies of oligonucleotides as models of unusual DNA structures Electrochemical detectros of DNA hybridization and their applications in DNA diagnostics
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	391
http://linked.open...iv/tvurceVysledku	Fojta, Miroslav Havran, Luděk Vacek, Jan Cahová, Kateřina
http://linked.open...ain/vavai/riv/wos	000256908200028
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions
issn	1618-2642
number of pages	8 (xsd:int)

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