About: The three-dimensional structure of human interphase chromosomes is related to the transcriptome map

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The three-dimensional (3D) organization of the chromosomal fiber in the human interphase nucleus is an important but poorly understood aspect of gene regulation. Here we quantitatively analyze and compare the 3D structures of two types of genomic domains - ridges and antiridges - defined by the human transcriptome map. Our results reveal novel general aspects of 3D chromosome architecture that are related to genome structure and function. The three-dimensional (3D) organization of the chromosomal fiber in the human interphase nucleus is an important but poorly understood aspect of gene regulation. Here we quantitatively analyze and compare the 3D structures of two types of genomic domains - ridges and antiridges - defined by the human transcriptome map. Our results reveal novel general aspects of 3D chromosome architecture that are related to genome structure and function. (en) 3D organizace chromozómových vláken v lidském interfázním jádře je důležitým, ale málo prostudovaným aspektem regulace genů. Zde jsme kvantitativně analyzovali a srovnávali 3D strukturu dvou typů genomických domén - ridges a antiridges - definovaných lidskou transkripční mapou. Naše výsledky odhalily nové obecné aspekty chromozomální 3D architektury vzhledem ke struktuře genomu a funkci. (cs)
Title	The three-dimensional structure of human interphase chromosomes is related to the transcriptome map The three-dimensional structure of human interphase chromosomes is related to the transcriptome map (en) 3D struktura lidských interfázních chromozómů vzhledem k jejím transkripčním mapám (cs)
skos:prefLabel	The three-dimensional structure of human interphase chromosomes is related to the transcriptome map The three-dimensional structure of human interphase chromosomes is related to the transcriptome map (en) 3D struktura lidských interfázních chromozómů vzhledem k jejím transkripčním mapám (cs)
skos:notation	RIV/68081707:_____/07:00090345!RIV08-AV0-68081707
http://linked.open.../vavai/riv/strany	4475;4487
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1K04112), Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika	12
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Ondřej, Vladan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	455146
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/07:00090345
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	in situ hybridization; human cell-nuclei; human genome (en)
http://linked.open.../riv/klicoveSlovo	in situ hybridization human cell-nuclei human genome
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[50EB3FED008C]
http://linked.open...i/riv/nazevZdroje	Molecular and Cellular Biology
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Modification of histones in chromatin regions with increased and reduced expression
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	27
http://linked.open...iv/tvurceVysledku	Ondřej, Vladan Gierman, H. J. Versteeg, R. Goetze, S. Giromus, O. Indemans, M. H. G. Koster, J. Mateos-Langerak, J. de Leeuw, W. van Driel, R.
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions
issn	0270-7306
number of pages	13 (xsd:int)

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