About: Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites

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About: Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We investigated the nuclear arrangement of HP1alpha, HP1gamma and TIF1beta proteins during differentiation of embryonic carcinoma P19 cells into primitive endoderm and into the neural pathway. Additionally, the differentiation potential of trichostatin A (TSA) and 5-deoxyazacytidine (5-dAzaC) was studied. Our findings showed that the nuclear arrangement of HP1 subtypes and is differentiation-specific, and seems to be more important than changes in the levels of these proteins, which were relatively stable during all the induced differentiation processes. We investigated the nuclear arrangement of HP1alpha, HP1gamma and TIF1beta proteins during differentiation of embryonic carcinoma P19 cells into primitive endoderm and into the neural pathway. Additionally, the differentiation potential of trichostatin A (TSA) and 5-deoxyazacytidine (5-dAzaC) was studied. Our findings showed that the nuclear arrangement of HP1 subtypes and is differentiation-specific, and seems to be more important than changes in the levels of these proteins, which were relatively stable during all the induced differentiation processes. (en) V experimentech jsme zkoumali jaderné uspořádání HP1alfa, HP1beta, HP1gama and TIF1beta proteinů během diferenciace embryonálních nádorových buněk P19 do primitivního endodermu a neurálním směrem. Diferenciační potenciál trichostatinu A (TSA) a 5-deoxyazacytidinu (5-dAzaC) byl dále studován. Zjistili jsme, že jaderné uspořádání HP1 subtypů a faktoru TIF1beta je diferenciačně specifické a zdá se být důležitější než množství syntetizovaných proteinů, které bylo relativně stejné během všech indukovaných diferenciačních procesů. (cs)
Title	Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites Diferenciačně-specifická asociace HP1alfa a HP1beta s chromocentra koreluje s klastrováním TIF1beta v těchto místech (cs) Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites (en)
skos:prefLabel	Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites Diferenciačně-specifická asociace HP1alfa a HP1beta s chromocentra koreluje s klastrováním TIF1beta v těchto místech (cs) Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites (en)
skos:notation	RIV/68081707:_____/07:00082872!RIV07-AV0-68081707
http://linked.open.../vavai/riv/strany	375;388
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1QS500040508), P(GA204/06/0978), P(GP524/03/P171), P(IAA5004306), P(LC535), Z(AV0Z50040507)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2007
http://linked.open...aciTvurceVysledku	Kozubík, Alois Bártová, Eva Kozubek, Stanislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	417301
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/07:00082872
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	HP1 proteiny; TIF1beta; chromocentry (en)
http://linked.open.../riv/klicoveSlovo	HP1 proteiny TIF1beta chromocentry
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[DABCA78083FA]
http://linked.open...i/riv/nazevZdroje	Histochemistry and Cell Biology
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Methylation of histone H3 as a prognostic marker of chronic myeloid leukemia remission Chromosome dynamics and organization during the cell cycle in normal and pathologic conditions Postranslational modifications of histones after cell treatment by inhibitors of histone deacetylases and during induction of cell differentiation Mechanisms driving neural differentiation in mouse embryonic stem cells in vitro Human genome structure
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	127
http://linked.open...iv/tvurceVysledku	Bártová, Eva Kozubík, Alois Kozubek, Stanislav Pacherník, J.
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems
issn	0948-6143
number of pages	14 (xsd:int)

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