About: Beta-Naphthoflavone and 3'-methoxy-4'-nitroflavone exert ambiguous effects on Ah receptor-dependent cell proliferation and gene expression in rat liver 'stem-like' cells

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About: Beta-Naphthoflavone and 3'-methoxy-4'-nitroflavone exert ambiguous effects on Ah receptor-dependent cell proliferation and gene expression in rat liver 'stem-like' cells Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In the present study we show that partial agonists/antagonists of AhR can increase cell proliferation rate and AhR-dependent genes expression in both cell type- and gene-specific manner. The specificity of effects of flavones on diverse AhR targets should be taken into account, when studying AhR signaling using presumed AhR antagonists. In the present study we show that partial agonists/antagonists of AhR can increase cell proliferation rate and AhR-dependent genes expression in both cell type- and gene-specific manner. The specificity of effects of flavones on diverse AhR targets should be taken into account, when studying AhR signaling using presumed AhR antagonists. (en) V této studii jsme prokázali, že částeční agonisté/antagonisté AhR mohou posilovat buněčnou proliferaci a genovou expresi závislou na ahR způsobem, který závisí jak na buněčném typu, tak na konkrétním genu. Tato specifičnost účinků flavonů na různé cíle ahR by měla být brána v potaz, pokud jsou využívány ke studiu signální dráhy ahR jako antagonisté. (cs)
Title	Beta-Naphthoflavone and 3'-methoxy-4'-nitroflavone exert ambiguous effects on Ah receptor-dependent cell proliferation and gene expression in rat liver 'stem-like' cells Beta-Naphthoflavone and 3'-methoxy-4'-nitroflavone exert ambiguous effects on Ah receptor-dependent cell proliferation and gene expression in rat liver 'stem-like' cells (en) Beta-Naftoflavon a 3'-methoxy-4'-nitroflavon mají víceznačné účinky na AhR-závislou buněčnou proliferaci a genovou expresi v jaterních progenitorových buňkách potkana (cs)
skos:prefLabel	Beta-Naphthoflavone and 3'-methoxy-4'-nitroflavone exert ambiguous effects on Ah receptor-dependent cell proliferation and gene expression in rat liver 'stem-like' cells Beta-Naphthoflavone and 3'-methoxy-4'-nitroflavone exert ambiguous effects on Ah receptor-dependent cell proliferation and gene expression in rat liver 'stem-like' cells (en) Beta-Naftoflavon a 3'-methoxy-4'-nitroflavon mají víceznačné účinky na AhR-závislou buněčnou proliferaci a genovou expresi v jaterních progenitorových buňkách potkana (cs)
skos:notation	RIV/68081707:_____/07:00081056!RIV07-AV0-68081707
http://linked.open.../vavai/riv/strany	1622;1634
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA524/06/0517), P(KJB6004407), Z(AV0Z50040507)
http://linked.open...iv/cisloPeriodika	10
http://linked.open...vai/riv/dodaniDat	2007
http://linked.open...aciTvurceVysledku	Kozubík, Alois Vondráček, Jan Procházková, Jiřina Švihálková-Šindler, Lenka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	411579
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/07:00081056
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	flavony; aryl hydrocarbon receptor; cell proliferation (en)
http://linked.open.../riv/klicoveSlovo	aryl hydrocarbon receptor cell proliferation flavony
http://linked.open...odStatuVydavatele	IE - Irsko
http://linked.open...ontrolniKodProRIV	[55650102B198]
http://linked.open...i/riv/nazevZdroje	Pharmacology
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Mechanisms of disruption of cell-to-cell communication and regulation of cell proliferation in liver cells Interactions of genotoxic and non-genotoxic effects of polycyclic aromatic hydrocarbons in regulation of cell proliferation
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	73
http://linked.open...iv/tvurceVysledku	Kozubík, Alois Krčmář, P. Machala, M. Vondráček, Jan Zatloukalová, Jiřina Šindlerová, Lenka
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems
issn	0031-7012
number of pages	13 (xsd:int)

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