About: Activation of ERK1/2 and p38 kinases by polycyclic aromatic hydrocarbons in rat liver epithelial cells is associated with induction of apoptosis

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About: Activation of ERK1/2 and p38 kinases by polycyclic aromatic hydrocarbons in rat liver epithelial cells is associated with induction of apoptosis Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Prezentovaná data ukazují, že ERK1/2 i p38 jsou aktivovány v odpovědi na působení dibenzo[al]pyrenu (DBalP) a že se mohou podílet na regulaci buněčné odpovědi na poškození DNA způsobené DBalP. Na druhou stranu, ani jedna z těchto kináz se nepodílí na uvolnění z kontaktní inhibice prostřednictvím PAU. (cs) The present data suggest that both ERK1/2 and p38 are activated in response to dibenzo[a,l]pyrenu (DBalP) and that they might be involved in regulation of cellular response to DNA damage induced by DBalP. On the other hand, neither kinase is involved in the release from contact inhibition induced by PAHs. The present data suggest that both ERK1/2 and p38 are activated in response to dibenzo[a,l]pyrenu (DBalP) and that they might be involved in regulation of cellular response to DNA damage induced by DBalP. On the other hand, neither kinase is involved in the release from contact inhibition induced by PAHs. (en)
Title	Activation of ERK1/2 and p38 kinases by polycyclic aromatic hydrocarbons in rat liver epithelial cells is associated with induction of apoptosis Activation of ERK1/2 and p38 kinases by polycyclic aromatic hydrocarbons in rat liver epithelial cells is associated with induction of apoptosis (en) Aktivace kináz ERK1/2 a p38 polycyklickými aromatickými uhlovodíky v jaterních epiteliálních buňkách potkana souvisí s indukcí apoptózy (cs)
skos:prefLabel	Activation of ERK1/2 and p38 kinases by polycyclic aromatic hydrocarbons in rat liver epithelial cells is associated with induction of apoptosis Activation of ERK1/2 and p38 kinases by polycyclic aromatic hydrocarbons in rat liver epithelial cells is associated with induction of apoptosis (en) Aktivace kináz ERK1/2 a p38 polycyklickými aromatickými uhlovodíky v jaterních epiteliálních buňkách potkana souvisí s indukcí apoptózy (cs)
skos:notation	RIV/68081707:_____/06:00048081!RIV07-AV0-68081707
http://linked.open.../vavai/riv/strany	198;208
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GP525/01/D076), Z(AV0Z50040507), Z(MZE0002716201)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2007
http://linked.open...aciTvurceVysledku	Chramostová, Kateřina Kozubík, Alois Vondráček, Jan Andrysík, Zdeněk Hofmanová, Jiřina
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	464065
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/06:00048081
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	MAP kinases; PAHs; apoptosis (en)
http://linked.open.../riv/klicoveSlovo	PAHs apoptosis MAP kinases
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[C313D3C63D9E]
http://linked.open...i/riv/nazevZdroje	Toxicology and Applied Pharmacology
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Activation of MAP protein kinase pathways by polycyclic aromatic hydrocarbons in vitro - a potential nongenotoxic mechanism underlying the effects of environmen
http://linked.open...UplatneniVysledku	2006
http://linked.open...v/svazekPeriodika	211
http://linked.open...iv/tvurceVysledku	Andrysík, Zdeněk Hofmanová, Jiřina Kozubík, Alois Machala, M. Vondráček, Jan Chramostová, Kateřina
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Zdravá zvířata a bezpečné potraviny jako základ pro zdraví lidí
issn	0041-008X
number of pages	11 (xsd:int)

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