About: Modifications of DNA by platinum complexes. Relation to resistance of tumors to platinum antitumor drugs     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
Description
  • Význam platinových chemoterapeutik v léčbě nádorů je podložen klinickým úspěchem cisplatiny a jejích přímých analog. I přesto se však může vyskytnout k těmto léčivům rezistence, způsobená různými faktory. Tento přehled je zaměřen na mechanismy rezistence a citlivosti nádorů ke klasické cisplatin, související s vazbou na DNA. Diskutujeme také molekulární mechanismus rezistence a citlivosti nádorů vůči novým sloučeninám, které byly připraveny s cílem překonat rezistenci nádorů k dosud používaným platinovým léčivům. (cs)
  • The importance of platinum drugs in cancer chemotherapy is underscored by the clinical success of cisplatin and its analogues. Nevertheless, drug resistance can occur by several ways. This review focuses on mechanisms of resistance and sensitivity of tumors to conventional cisplatin associated with DNA modification. We also discuss molecular mechanisms underlying resistance and sensitivity of tumors to the new platinum compounds synthesized with the goal to overcome resistance of tumors to established platinum drugs.
  • The importance of platinum drugs in cancer chemotherapy is underscored by the clinical success of cisplatin and its analogues. Nevertheless, drug resistance can occur by several ways. This review focuses on mechanisms of resistance and sensitivity of tumors to conventional cisplatin associated with DNA modification. We also discuss molecular mechanisms underlying resistance and sensitivity of tumors to the new platinum compounds synthesized with the goal to overcome resistance of tumors to established platinum drugs. (en)
Title
  • Modifications of DNA by platinum complexes. Relation to resistance of tumors to platinum antitumor drugs
  • Modifications of DNA by platinum complexes. Relation to resistance of tumors to platinum antitumor drugs (en)
  • Modifikace DNA komplexy platiny. Vztah k rezistenci nádorů vůči platinovým cytostatikům (cs)
skos:prefLabel
  • Modifications of DNA by platinum complexes. Relation to resistance of tumors to platinum antitumor drugs
  • Modifications of DNA by platinum complexes. Relation to resistance of tumors to platinum antitumor drugs (en)
  • Modifikace DNA komplexy platiny. Vztah k rezistenci nádorů vůči platinovým cytostatikům (cs)
skos:notation
  • RIV/68081707:_____/05:00022144!RIV06-AV0-68081707
http://linked.open.../vavai/riv/strany
  • 131;146
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA305/05/2030), P(NR8562), Z(AV0Z50040507)
http://linked.open...iv/cisloPeriodika
  • -
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 530921
http://linked.open...ai/riv/idVysledku
  • RIV/68081707:_____/05:00022144
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • cisplatin; transplatin; new platinum drugs (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [3C9F002F6D1B]
http://linked.open...i/riv/nazevZdroje
  • Drug Resistance Updates
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 8
http://linked.open...iv/tvurceVysledku
  • Brabec, Viktor
  • Kašpárková, Jana
http://linked.open...n/vavai/riv/zamer
issn
  • 1368-7646
number of pages
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software