About: Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Ovlivnění buněk lidského adenokarcinomu kolonu HT-29 mastnými kyselinami arachidonovou nebo dokosahexaenovou oslabovalo zástavu buněčného cyklu indukovanou butyrátem sodným (NaBt), která byla spojena s modulací exprese proteinu p27Kip1, nikoli však p21Cip1/WAF1 . Na druhé straně, mastné kyseliny zcitlivovaly buňky HT-29 k apoptóze indukované NaBt. Pozorované účinky byly modulovány inhibitorem syntézy proteinů cykloheximidem a částečně revertovány antioxidantem Troloxem. (cs) Pre-treatment of human adenocarcinoma HT-29 cells with either arachidonic or docosahexaenoic fatty acids attenuated cell cycle arrest caused by sodium butyrate (NaBt) which was associated with modulation of p27Kip1, but not p21Cip1/WAF1 protein expression. On the other hand, fatty acids sensitized HT-29 cells to NaBt-induced apoptosis. The observed effects were modulated by the addition of a protein synthesis inhibitor, cycloheximide, and partially reversed by the antioxidant Trolox. Pre-treatment of human adenocarcinoma HT-29 cells with either arachidonic or docosahexaenoic fatty acids attenuated cell cycle arrest caused by sodium butyrate (NaBt) which was associated with modulation of p27Kip1, but not p21Cip1/WAF1 protein expression. On the other hand, fatty acids sensitized HT-29 cells to NaBt-induced apoptosis. The observed effects were modulated by the addition of a protein synthesis inhibitor, cycloheximide, and partially reversed by the antioxidant Trolox. (en)
Title	Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells Interakce vysoce nenasycených mastných kyselin a butyrátu sodného během apoptózy buněk lidského adenokarcinomu kolonu HT-29 (cs) Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells (en)
skos:prefLabel	Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells Interakce vysoce nenasycených mastných kyselin a butyrátu sodného během apoptózy buněk lidského adenokarcinomu kolonu HT-29 (cs) Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells (en)
skos:notation	RIV/68081707:_____/05:00001087!RIV06-AV0-68081707
http://linked.open.../vavai/riv/strany	40;51
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA525/01/0419), Z(AV0Z50040507)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Lojek, Antonín Kozubík, Alois Hofmanová, Jiřina Vaculová, Alena
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	525309
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/05:00001087
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	colon cancer; diet; butyrate (en)
http://linked.open.../riv/klicoveSlovo	butyrate colon cancer diet - livestock depredation - predator - prey density - scat analysis
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[DA3496061B1A]
http://linked.open...i/riv/nazevZdroje	European Journal of Nutrition
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Dietary lipid components in the regulation of cytokinetics of colonic epithelium
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	44
http://linked.open...iv/tvurceVysledku	Hofmanová, Jiřina Kozubík, Alois Lojek, Antonín Vaculová, Alena
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems
issn	1436-6207
number of pages	12 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software