About: Polyunsaturated fatty acids sensitize human colon adenocarcinoma HT-29 cells to death receptor-mediated apoptosis

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About: Polyunsaturated fatty acids sensitize human colon adenocarcinoma HT-29 cells to death receptor-mediated apoptosis Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Ovlivnění buněk lidského adenokarcinomu kolonu HT-29 mastnými kyselinami arachidonovou nebo dokosahexaenovou zvyšujícími oxidativní stres zcitlivovalo tyto buňky k apoptóze indukované TNF-alpha nebo anti-Fas monoklonální protilátkou. Zvýšené množství plovoucích buněk, buněk v subG0/G1 fázi i buněk s apoptickou morfologií u kyselinami ovlivněné populace bylo posíleno inhibicí syntézy proteinů cykloheximidem. (cs) Pre-treatment of colon adenocarcinoma HT-29 cells with arachidonic or docosahexaenoic fatty acids which induced oxidative stress sensitized these cells to apoptosis induced by TNF-alpha or anti-Fas monoclonal antibody. The higher amount of floating cells, subG0/G1 population and apoptotic cells detected in pre-treated cells was potentiated by inhibition of protein synthesis by cycloheximide. Pre-treatment of colon adenocarcinoma HT-29 cells with arachidonic or docosahexaenoic fatty acids which induced oxidative stress sensitized these cells to apoptosis induced by TNF-alpha or anti-Fas monoclonal antibody. The higher amount of floating cells, subG0/G1 population and apoptotic cells detected in pre-treated cells was potentiated by inhibition of protein synthesis by cycloheximide. (en)
Title	Polyunsaturated fatty acids sensitize human colon adenocarcinoma HT-29 cells to death receptor-mediated apoptosis Interakce vysoce nenasycených mastných kyselin a butyrátu sodného během apoptózy buněk lidského adenokarcinomu kolonu HT-29 (cs) Polyunsaturated fatty acids sensitize human colon adenocarcinoma HT-29 cells to death receptor-mediated apoptosis (en)
skos:prefLabel	Polyunsaturated fatty acids sensitize human colon adenocarcinoma HT-29 cells to death receptor-mediated apoptosis Interakce vysoce nenasycených mastných kyselin a butyrátu sodného během apoptózy buněk lidského adenokarcinomu kolonu HT-29 (cs) Polyunsaturated fatty acids sensitize human colon adenocarcinoma HT-29 cells to death receptor-mediated apoptosis (en)
skos:notation	RIV/68081707:_____/05:00001076!RIV06-GA0-68081707
http://linked.open.../vavai/riv/strany	33;41
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA524/04/0895)
http://linked.open...iv/cisloPeriodika	-
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Kozubík, Alois Hofmanová, Jiřina Vaculová, Alena
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	536712
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/05:00001076
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	colon cancer; diet; butyrate (en)
http://linked.open.../riv/klicoveSlovo	butyrate colon cancer diet - livestock depredation - predator - prey density - scat analysis
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[B6D382999DAD]
http://linked.open...i/riv/nazevZdroje	Cancer letters
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Mechanisms of the cell death induced by dietary lipid components and endogenous apoptotic regulators in colon epithelial cells
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	218
http://linked.open...iv/tvurceVysledku	Hofmanová, Jiřina Kozubík, Alois Vaculová, Alena
issn	0304-3835
number of pages	9 (xsd:int)

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