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rdf:type
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Description
| - Binding of active, latent and in vitro-activated p53 protein to DNA fragments globally modified by antitumor cisplatin was studied using electrophoretic mobility shift assay in agarose gels and immunoblotting analysis. Both latent and active p53 forms bound to platinated random sequences of DNA with a higher affinity than to unmodified DNA. The latent form exhibited a more pronounced selectivity for platinated DNA than the active p53.
- Binding of active, latent and in vitro-activated p53 protein to DNA fragments globally modified by antitumor cisplatin was studied using electrophoretic mobility shift assay in agarose gels and immunoblotting analysis. Both latent and active p53 forms bound to platinated random sequences of DNA with a higher affinity than to unmodified DNA. The latent form exhibited a more pronounced selectivity for platinated DNA than the active p53. (en)
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Title
| - Recognition of DNA modified by antitumor cisplatin by 'latent' and 'active' protein p53.
- Recognition of DNA modified by antitumor cisplatin by 'latent' and 'active' protein p53. (en)
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skos:prefLabel
| - Recognition of DNA modified by antitumor cisplatin by 'latent' and 'active' protein p53.
- Recognition of DNA modified by antitumor cisplatin by 'latent' and 'active' protein p53. (en)
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skos:notation
| - RIV/68081707:_____/03:17033016!RIV/2004/AV0/A17004/N
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA204/02/0734), P(GA301/00/P094), P(GA301/02/0831), P(GA305/01/0418), P(GA305/02/1552), P(IBS5004009), P(NC5343), P(NC7131), P(NL6058), Z(AV0Z5004920)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/68081707:_____/03:17033016
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - tumor suppressor protein p53; latent p53; antitumor drugs (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...ocetUcastnikuAkce
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http://linked.open...nichUcastnikuAkce
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Brabec, Viktor
- Brázdová, Marie
- Kašpárková, Jana
- Paleček, Emil
- Pospíšilová, Š.
- Pivoňková, Hana
- Kovářová, Lucie
- Vojtěšek, B.
- Fojta, Miloslav
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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