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Description
| - A series of low-molecular-weight mono- and dihydroxylated PCBs (HO-PCBs), 2-(chlorophenyl)-1,4-benzoquinones (BQs) and 1,4-hydroquinones (HQs) were tested for their nongenotoxic potencies in several established in vitro cellular models. The data presented here show that both the low-molecular-weight PCB metabolites and the persistent HO-PCBs are capable of multiple nongenotoxic modes of action, including significant dioxin-like activity, modulation of ER-mediated activity and promotional effects associated with inhibition of intercellular communication.
- A series of low-molecular-weight mono- and dihydroxylated PCBs (HO-PCBs), 2-(chlorophenyl)-1,4-benzoquinones (BQs) and 1,4-hydroquinones (HQs) were tested for their nongenotoxic potencies in several established in vitro cellular models. The data presented here show that both the low-molecular-weight PCB metabolites and the persistent HO-PCBs are capable of multiple nongenotoxic modes of action, including significant dioxin-like activity, modulation of ER-mediated activity and promotional effects associated with inhibition of intercellular communication. (en)
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Title
| - Comparison of relative toxic potencies of hydroxylated PCBs and quinones in hepatic and mammary cell lines.
- Comparison of relative toxic potencies of hydroxylated PCBs and quinones in hepatic and mammary cell lines. (en)
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skos:prefLabel
| - Comparison of relative toxic potencies of hydroxylated PCBs and quinones in hepatic and mammary cell lines.
- Comparison of relative toxic potencies of hydroxylated PCBs and quinones in hepatic and mammary cell lines. (en)
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skos:notation
| - RIV/68081707:_____/02:17023192!RIV/2003/AV0/A17003/N
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/68081707:_____/02:17023192
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - hydroxylated PCBs; quinones; in vitro effects (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...v/mistoKonaniAkce
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http://linked.open...i/riv/mistoVydani
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http://linked.open...i/riv/nazevZdroje
| - Organohalogen Compounds, vol. 56: Dioxin 2002.
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...ocetUcastnikuAkce
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http://linked.open...nichUcastnikuAkce
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http://linked.open...UplatneniVysledku
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http://linked.open...iv/tvurceVysledku
| - Machala, M.
- Vondráček, Jan
- Bláha, L.
- Lehmler, H. J.
- Malmberg, T.
- Robertson, L. W.
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http://linked.open...vavai/riv/typAkce
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http://linked.open.../riv/zahajeniAkce
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http://linked.open...n/vavai/riv/zamer
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number of pages
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http://purl.org/ne...btex#hasPublisher
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https://schema.org/isbn
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