About: Chromatin structure in solid cancers and leukemic cells.     Goto   Sponge   NotDistinct   Permalink

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  • Gene loci (Rb1, N-myc, p53) and chromosomes (6, 13, X and others) were studied in selected human tumour cells. Fresh tissue or paraffin-embedded sections were used for chromatin analyses. Heterogeneity in the copy number of genetic elements was found in tumour cells and lymphocytes of the patients with diagnosed retinoblastoma. Our findings support an assertion that structural and functional modifications of chromatin are an important feature of carcinogenesis.
  • Gene loci (Rb1, N-myc, p53) and chromosomes (6, 13, X and others) were studied in selected human tumour cells. Fresh tissue or paraffin-embedded sections were used for chromatin analyses. Heterogeneity in the copy number of genetic elements was found in tumour cells and lymphocytes of the patients with diagnosed retinoblastoma. Our findings support an assertion that structural and functional modifications of chromatin are an important feature of carcinogenesis. (en)
Title
  • Chromatin structure in solid cancers and leukemic cells.
  • Chromatin structure in solid cancers and leukemic cells. (en)
skos:prefLabel
  • Chromatin structure in solid cancers and leukemic cells.
  • Chromatin structure in solid cancers and leukemic cells. (en)
skos:notation
  • RIV/68081707:_____/02:17023088!RIV/2003/GA0/A17003/N
http://linked.open.../vavai/riv/strany
  • 88;93
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA301/01/0186), P(IAB5004102), P(IBS5004010), Z(AV0Z5004920)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...dnocenehoVysledku
  • 640856
http://linked.open...ai/riv/idVysledku
  • RIV/68081707:_____/02:17023088
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • chromatin structure; chromosomal aberrations; retinoblastoma cells (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [C254EE861A8B]
http://linked.open...v/mistoKonaniAkce
  • Stockholm [SE]
http://linked.open...i/riv/mistoVydani
  • Manchester
http://linked.open...i/riv/nazevZdroje
  • QMC 2002: The Third Euroconference on Quantitative Molecular Cytogenetics.
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
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http://linked.open...iv/tvurceVysledku
  • Bártová, Eva
  • Kozubek, Stanislav
  • Lukášová, Emilie
  • Kozubek, M.
  • Jirsová, Pavla
  • Cafourková, Alena
  • Skalníková, M.
  • Koutná, I.
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
http://linked.open...n/vavai/riv/zamer
number of pages
http://purl.org/ne...btex#hasPublisher
  • European Commission
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